ALK-positive non-small-cell lung cancer
Clinical trials for ALK-positive non-small-cell lung cancer explained in plain language.
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Can a Two-Drug punch before surgery beat ALK-Positive lung cancer?
Cure Not yet recruitingThis trial is testing whether giving a combination of iruplaltinib and pemetrexed before surgery can shrink tumors in people with early-stage ALK-positive non-small cell lung cancer. The goal is to see if this pre-treatment improves the chance of removing all cancer during surger…
Matched conditions: ALK-POSITIVE NON-SMALL-CELL LUNG CANCER
Phase 2 • Sponsor: First Affiliated Hospital of Fujian Medical University • Aim: Cure
Last updated Aug 20, 2026 00:00 UTC
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Can a drug duo outsmart ALK-Positive lung cancer?
Disease control Not yet recruitingThis trial is testing whether combining two targeted therapies—lorlatinib and sacituzumab tirumotecan—can better control advanced ALK-positive non-small cell lung cancer when used as the first treatment. The study involves about 153 adults with locally advanced or metastatic dise…
Matched conditions: ALK-POSITIVE NON-SMALL-CELL LUNG CANCER
Phase 2 • Sponsor: Guangdong Association of Clinical Trials • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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New drug cocktail aims to outsmart resistant lung cancer
Disease control Not yet recruitingThis phase 4 trial tests whether combining two oral drugs—ensartinib and anlotinib—can shrink tumors or slow disease in people with ALK-positive non-small cell lung cancer that has become resistant to lorlatinib. About 80 adults with advanced (stage IIIB-IV) cancer will receive t…
Matched conditions: ALK-POSITIVE NON-SMALL-CELL LUNG CANCER
Phase 4 • Sponsor: Qiming Wang • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC