ALCOHOL-RELATED DISORDERS

This study tests whether a psychedelic drug called DMT, combined with talk therapy, can help people with alcohol use disorder drink less. About 63 adults with alcohol use disorder will receive either DMT or a placebo in a controlled setting. Researchers will check if the treatmen…

This early-stage study tests whether diclofenac, a common anti-inflammatory drug, can help people with alcohol use disorder by changing brain chemistry. Researchers will give 24 adults either a placebo or one of three doses of diclofenac to see if it reduces alcohol cravings and …

This study aims to understand how the brains of people with alcohol dependence differ from those without it. Researchers will use MRI scans and computer games to look at brain structure and activity. About 1,000 adults aged 18 and older will participate in a single visit. No trea…

This study tests a low-cost program called MINDSET for veterans with chronic health problems like heart disease or diabetes who smoke or drink too much. Participants receive a mailed packet with personalized health information and a short motivational phone call. The goal is to s…

This study follows 1500 adults to understand how the COVID-19 pandemic has changed their drinking habits and stress levels. Participants complete surveys online or by phone over 2 years, reporting on alcohol use, mental health, and quality of life. No treatments or medications ar…