Agitation
Clinical trials for Agitation explained in plain language.
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Hope for Alzheimer's agitation: new drug enters final testing
Symptom relief OngoingThis study tests whether masupirdine, a daily tablet, can safely reduce agitation in people with Alzheimer's dementia. About 375 participants will receive either masupirdine or a placebo. The main goal is to see if the drug improves agitation symptoms, which can include aggressio…
Matched conditions: AGITATION
Phase 3 • Sponsor: Suven Life Sciences Limited • Aim: Symptom relief
Last updated Sep 17, 2026 00:00 UTC
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Can a dissolvable film quiet ICU delirium?
Symptom relief CancelledThis phase 2 trial is testing whether a dissolvable film containing dexmedetomidine (BXCL501) can safely and effectively reduce agitation in adult ICU patients who have delirium. The study will compare four different starting doses of the drug against a placebo to find the best b…
Matched conditions: AGITATION
Phase 2 • Sponsor: BioXcel Therapeutics Inc • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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ER agitation study pulled before it began
Symptom relief CancelledThis study aimed to see if a dissolvable film placed under the tongue could quickly calm agitation in people with bipolar disorder or schizophrenia who come to the emergency room. The drug, BXCL501, is already approved for this use, but the study wanted to test it in the ER setti…
Matched conditions: AGITATION
Phase 4 • Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC