ADVANCED SOLID TUMOURS

This early-phase study tests a new drug called LM-168, alone or with another drug (toripalimab), in 87 adults with advanced solid tumours that have stopped responding to standard treatments. The goal is to check safety and find the best dose, and to see if the drugs can shrink tu…

This trial tests a new drug called UCB4594, an antibody that targets a protein (HLA-G) found on many cancer cells. The goal is to see if it helps the immune system attack tumors. It is for people with advanced solid tumors (like lung, breast, or colon cancer) that have not respon…

This study tests a new drug called PYX-201 combined with pembrolizumab in people with advanced solid tumors that have not responded to other treatments. The goal is to find the safest dose and see if the combination can shrink tumors or slow their growth. About 220 adults with ce…

This study tests a new drug called SIM0610 in adults with advanced solid tumors (cancers that have spread). The main goals are to check safety and find the right dose. About 260 people with certain cancers like lung, colon, head and neck, or liver cancer can join. The study has t…

This early-phase study tests a new drug called EBC-129, alone or with another drug (pembrolizumab), in people with advanced solid tumours that have stopped responding to standard treatments. The main goals are to check safety, find the best dose, and see if tumours shrink. About …

This early-phase study tests a new experimental drug called AZD9592, alone or with other cancer treatments, in people with advanced solid tumors (lung, head & neck, or colorectal cancers) that have not responded to standard therapy. The main goals are to check safety, find the ri…

This early-stage study tests a new drug called RC220 given together with a standard chemotherapy (doxorubicin) in adults with advanced solid tumours. The main goals are to find the safest dose and see if RC220 can protect the heart from doxorubicin's side effects. About 53 people…