ADVANCED SOFT-TISSUE SARCOMA
Clinical trials for ADVANCED SOFT-TISSUE SARCOMA explained in plain language.
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New combo therapy shows promise for rare sarcoma
Disease control OngoingThis study tests a combination of two drugs, HDM201 and pazopanib, in people with advanced soft tissue sarcoma that has spread. The goal is to find the safest dose and see if the combo can help control the cancer. About 47 adults with a specific genetic type (P53 wild-type) will …
Matched conditions: ADVANCED SOFT-TISSUE SARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Centre Leon Berard • Aim: Disease control
Last updated May 26, 2026 08:58 UTC
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New combo therapy shows promise for rare sarcoma
Disease control OngoingThis study tests whether adding two immunotherapy drugs (zalifrelimab and balstilimab) to standard chemotherapy (doxorubicin) can help people with advanced or metastatic soft tissue sarcoma live longer without their cancer growing. About 65 adults aged 18-100 who have not had pri…
Matched conditions: ADVANCED SOFT-TISSUE SARCOMA
Phase: PHASE2 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Promising drug combo targets rare sarcoma in early trial
Disease control OngoingThis study tests a new combination of two drugs, lurbinectedin and doxorubicin, for people with advanced leiomyosarcoma, a rare soft tissue cancer. The first part finds a safe dose, and the second part compares the combination to lurbinectedin alone to see which works better. Abo…
Matched conditions: ADVANCED SOFT-TISSUE SARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 13, 2026 16:03 UTC