Advanced clear cell renal cell carcinoma
Clinical trials for Advanced clear cell renal cell carcinoma explained in plain language.
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Can a Patient's own immune cells beat advanced kidney cancer?
Cure Not yet recruitingThis early-stage trial is testing an experimental therapy called HS-IT101 for people with advanced clear cell renal cell carcinoma, a type of kidney cancer. The treatment involves collecting immune cells from the patient's tumor, multiplying them in the lab, and infusing them bac…
Matched conditions: ADVANCED CLEAR CELL RENAL CELL CARCINOMA
Phase 1 • Sponsor: Qingdao Sino-Cell Biomedicine Co., Ltd. • Aim: Cure
Last updated Aug 20, 2026 00:00 UTC
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Can a drug combo prime the immune system to fight kidney cancer before surgery?
Disease control Not yet recruitingThis phase II trial is testing whether giving toripalimab (an immunotherapy) plus axitinib (a targeted therapy) for about 12 weeks before a possible delayed kidney removal can help control advanced clear cell kidney cancer. The study enrolls adults whose primary kidney tumor is s…
Matched conditions: ADVANCED CLEAR CELL RENAL CELL CARCINOMA
Phase 2 • Sponsor: Fudan University • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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Personalized combo therapy aims to overcome drug resistance in kidney cancer
Disease control Not yet recruitingThis study tests whether adding the cholesterol drug atorvastatin to standard targeted therapy (axitinib) and immunotherapy (toripalimab) can help people with advanced kidney cancer who are not responding well to treatment. The drug combination is guided by lab tests on patient-d…
Matched conditions: ADVANCED CLEAR CELL RENAL CELL CARCINOMA
Phase 1/2 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New combo tackles kidney cancer that came back after immunotherapy
Disease control Not yet recruitingThis study tests whether combining two drugs, pembrolizumab and lenvatinib, can help people with advanced kidney cancer (clear cell type) whose cancer returned after prior immunotherapy. About 108 adults will receive the combination to see if it shrinks tumors or delays cancer gr…
Matched conditions: ADVANCED CLEAR CELL RENAL CELL CARCINOMA
Phase 2 • Sponsor: Gruppo Oncologico Italiano di Ricerca Clinica • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Cold sore virus modified to fight kidney cancer in new trial
Disease control Not yet recruitingThis phase 2 trial tests a combination of RP2 (a modified herpes simplex virus that targets and destroys tumor cells) and tivozanib (a drug that blocks tumor blood vessel growth) in 35 patients with metastatic kidney cancer that worsened after immunotherapy. The goal is to see if…
Matched conditions: ADVANCED CLEAR CELL RENAL CELL CARCINOMA
Phase 2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New immunotherapy combo aims to fight advanced kidney cancer
Disease control Not yet recruitingThis study tests a combination of two drugs—envafolimab (an immunotherapy injection) and axitinib (a targeted therapy pill)—as a first treatment for people with advanced kidney cancer that has spread or cannot be removed. About 30 participants will receive the treatment for up to…
Matched conditions: ADVANCED CLEAR CELL RENAL CELL CARCINOMA
Phase 2 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 26, 2026 14:32 UTC