Acute chest syndrome
Clinical trials for Acute chest syndrome explained in plain language.
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Could a Low-Dose arthritis drug ease a dangerous sickle cell complication?
Disease control Recruiting nowThis phase 2 trial is testing whether a single low dose of tocilizumab, a drug that blocks inflammation, can help people with sickle cell disease who develop acute chest syndrome—a serious lung complication. Researchers will enroll 200 patients aged 12 and older and track their o…
Matched conditions: ACUTE CHEST SYNDROME
Phase 2 • Sponsor: University of Chicago • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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Can one infusion speed recovery from sickle cell lung crisis?
Disease control Recruiting nowThis study tests whether a single dose of tocilizumab, an anti-inflammatory drug, can help children and adults with sickle cell disease recover faster from acute chest syndrome—a serious lung condition. Participants receive either the drug or a placebo, and researchers measure ho…
Matched conditions: ACUTE CHEST SYNDROME
Phase 3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Kidney test could unlock better pain relief for sickle cell patients in crisis
Knowledge-focused Recruiting nowThis study looks at how quickly the kidneys clear morphine in sickle cell patients having a painful crisis. Researchers will measure kidney function and morphine levels in 100 intensive care patients to see if higher doses are needed for effective pain relief. The goal is to pers…
Matched conditions: ACUTE CHEST SYNDROME
Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC