Actinic keratoses
Clinical trials for Actinic keratoses explained in plain language.
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Can a Two-Drug cream clear precancerous skin spots even when immunity is suppressed?
Disease control Not yet recruitingThis trial tests a topical cream combining 5-fluorouracil and calcipotriene as a field treatment for actinic keratoses, which are rough, precancerous skin spots caused by sun damage. Researchers will compare how well the cream clears these spots in 32 people with normal immune fu…
Matched conditions: ACTINIC KERATOSES
Sponsor: Cedars-Sinai Medical Center • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Light therapy vs chemical peels: which zaps precancerous spots better?
Disease control Not yet recruitingThis study compares two treatments for actinic keratoses—rough, scaly spots that can turn into skin cancer—on the arms. One treatment uses a light-sensitizing gel followed by blue light (photodynamic therapy), while the other uses a two-step chemical peel. About 60 adults with sp…
Matched conditions: ACTINIC KERATOSES
Phase 2 • Sponsor: Northwestern University • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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Freeze then ointment: new combo tackles precancerous skin spots
Disease control Not yet recruitingThis study tests whether freezing precancerous skin spots (cryotherapy) followed by a medicated ointment (tirbanibulin) works better than freezing alone for actinic keratosis on the scalp and forehead. About 59 adults with at least 8 spots will receive the combo treatment or a pl…
Matched conditions: ACTINIC KERATOSES
Phase 3 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC