Young-onset Parkinson disease
MONDO:0017279A form of Parkinson disease (PD) characterized by an age of onset between 21-45 years, rigidity, painful cramps followed by tremor, bradykinesia, dystonia, gait complaints and falls, and other non-motor symptoms. A slow disease progression and a more pronounced response to dopaminergic therapy are also observed in most YOPD forms.
Also known as: YOPD, early-onset Parkinson disease, early-onset Parkinson's disease
23 clinical trials for this condition and its sub-types, 9 tagged with Young-onset Parkinson disease itself.
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Sub-types of Young-onset Parkinson disease
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Parkinson disease 10 0 trials
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Parkinson disease 12 0 trials
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Early-onset Parkinson disease 20 0 trials
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Juvenile-onset Parkinson disease 0 trials
3 sub-types
- Kufor-Rakeb syndrome 0 trials Sub-types →
- Parkinson disease 19B, early-onset 0 trials
- Juvenile onset Parkinson disease 19A 0 trials
Most studied deeper sub-types
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Scientists dig into DNA to unlock secrets of early Parkinson's
Knowledge-focused CompletedThis completed study looked at 31 people with early-onset Parkinson's disease (starting before age 50) and their family members to find genetic causes. Researchers collected blood and skin samples to study DNA and create cell lines. The goal was to better understand which gene mu…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Smart sensors could revolutionize Parkinson's monitoring
Knowledge-focused CompletedThis study used body-worn sensors to track movement in 132 people with early, untreated Parkinson's disease over 12 months. The goal was to see if digital measurements could accurately measure disease progression and match standard clinical assessments. The findings may help deve…
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC