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Wilms tumor 1
MONDO:0008679An autosomal disorder due to pathogenic variants in the WT1 gene leading to an increased risk Wilms tumor and genitourinary abnormalities incorporating Denys-Drash syndrome and Frasier syndrome.
Also known as: Wilms' tumor, Wilms' tumour, renal Wilms tumor, renal Wilms tumour, WT1-related Wilms tumor predisposition, Wilms tumor 1, Wilms tumor type 1, Wilms tumor, autosomal dominant, somatic mutation
2733 clinical trials for this condition and its sub-types, 4 tagged with Wilms tumor 1 itself.
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New hope for kids with tough cancers: GAIA-102 trial launches
Disease control Recruiting nowThis early-stage trial tests a new drug called GAIA-102 in children whose neuroblastoma or other solid tumors have not responded to standard treatments. The study has four groups, testing GAIA-102 alone or combined with other cancer drugs. The main goal is to check safety and fin…
Phase 1 • Sponsor: Kyushu University • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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Could a cancer drug that blocks a key protein help kids with relapsed wilms tumor?
Disease control Recruiting nowThis phase II trial is testing the drug selinexor in people with Wilms tumor, rhabdoid tumor, MPNST, or other solid tumors that have returned or not responded to treatment. Selinexor works by blocking a protein called XPO1, which is often overactive in these cancers. The study ai…
Phase 2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Can african hospitals follow the rules for treating childhood kidney cancer?
Knowledge-focused Recruiting nowThis study looks at how well hospitals in Africa follow recommended treatment steps for children with a type of kidney cancer called nephroblastoma. Researchers will check if doctors correctly diagnose the disease, give the right treatments, and track how children recover. The go…
Sponsor: French Africa Pediatric Oncology Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC