Wallerian degeneration

MONDO:0043280

A condition caused by degeneration, atrophy, and destruction of the distal part of a nerve fiber's axon and myelin, when continuity with the neural cell nucleus has been severed due to injury. Signs and symptoms include muscle weakness, altered sensation, and limb numbness.

Also known as: Wallerian Degeneration, Degeneration, Wallerian, Wallerian degeneration of the pyramidal tract

1 clinical trial for this condition and its sub-types, 1 tagged with Wallerian degeneration itself.

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↑ Nervous system disorder (26588)

Including sub-types (1) Tagged with Wallerian degeneration (1)

Not yet recruiting 1

Freezing away phantom pain: new study tests two Nerve-Freezing techniques for amputees

Symptom relief Not yet recruiting

This study tests two ways to freeze painful nerve endings (neuromas) in people who lost limbs in combat. One method freezes the nerve right at the painful spot, the other freezes it further up the nerve. The goal is to see which provides better pain relief. Fifty adults with chro…

Sponsor: Ukrainian Society of Regional Anesthesia and Pain Therapy • Aim: Symptom relief

Last updated Jun 27, 2026 13:00 UTC

Wallerian degeneration

Where it sits in the disease tree

Freezing away phantom pain: new study tests two Nerve-Freezing techniques for amputees