Van der Woude syndrome

MONDO:0019508

Van der Woude syndrome (VWS) is a rare congenital genetic dysmorphic syndrome characterized by paramedian lower-lip fistulae, cleft lip with or without cleft palate, or isolated cleft palate.

Also known as: VWS, cleft lip/palate with mucous cysts of lower lip, lip-pit syndrome, LPS, cleft lip and/or palate with mucous cysts of lower lip, lip pit syndrome

8 clinical trials for this condition and its sub-types, 8 tagged with Van der Woude syndrome itself.

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Where it sits in the disease tree

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Part of

↑ Hereditary disease (18235) ↑ Multiple congenital anomalies/dysmorphic syndrome without intellectual disability (163) ↑ IRF6-related condition (8)

Sub-types of Van der Woude syndrome

Van der Woude syndrome 1 0 trials
Van der Woude syndrome 2 0 trials

Including sub-types (8) Tagged with Van der Woude syndrome (8)

Trials to join now! 3 Not yet recruiting 1 Not yet finished but already full! 1 Completed 3

Could a gentler cleaning method make cavity sealants last longer?

Prevention Not yet recruiting

This trial tests whether cleaning the chewing surfaces of children's teeth with a fine erythritol powder spray (Guided Biofilm Therapy) before applying a protective sealant helps the sealant stay in place longer than the standard rotary-brush polishing. Each child aged 6–10 will …

Sponsor: Marmara University • Aim: Prevention

Last updated Jul 26, 2026 00:00 UTC

Van der Woude syndrome

Where it sits in the disease tree

Could a gentler cleaning method make cavity sealants last longer?