Urticaria
MONDO:0005492A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.
Also known as: hives, urticaria, urticaria (disease), Urticarias
165 clinical trials for this condition and its sub-types, 28 tagged with Urticaria itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Urticaria
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Angioedema 19 trials · 66 incl. sub-types
3 sub-types
- Hereditary angioedema 58 trials · 60 incl. sub-types Sub-types →
- Acquired angioedema 2 trials · 3 incl. sub-types Sub-types →
- Non-histaminic angioedema 2 trials
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Idiopathic urticaria 0 trials · 66 incl. sub-types
2 sub-types
- Chronic idiopathic urticaria 65 trials
- Acute idiopathic urticaria 1 trial
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Chronic urticaria 12 trials · 20 incl. sub-types
1 sub-type
- Chronic inducible urticaria 8 trials
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Physical urticaria 3 trials · 15 incl. sub-types
3 sub-types
- Familial dermatographia 12 trials
- Cholinergic urticaria 2 trials
- Vibratory urticaria 0 trials · 2 incl. sub-types Sub-types →
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Cold urticaria 10 trials
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Allergic urticaria 3 trials · 5 incl. sub-types
1 sub-type
- Non-histaminic angioedema 2 trials
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Cutaneous mastocytosis 1 trial
3 sub-types
- Cutaneous mastocytoma 0 trials Sub-types →
- Diffuse cutaneous mastocytosis 0 trials Sub-types →
- Maculopapular cutaneous mastocytosis 0 trials Sub-types →
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Urticaria, aquagenic 1 trial
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Melkersson-Rosenthal syndrome 0 trials
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Autoimmune urticaria 0 trials
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Papular urticaria 0 trials
Most studied deeper sub-types
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Could a histamine shot tame chronic hives?
Disease control Recruiting nowThis study looks at how well an injection called Immunoglobulin-Histamine complex (IHC, brand name Histoglob) works for people with chronic urticaria, or long-term hives. Researchers will track 600 patients in India to see if the treatment reduces hives and the need for other all…
Sponsor: Bharat Serums and Vaccines Limited • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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New drug hope for stubborn hives patients
Disease control Expanded accessThis program provides remibrutinib, an experimental drug, to adults with chronic spontaneous urticaria (long-term hives) that haven't improved with antihistamines or omalizumab. Participants take the drug as prescribed to help control their symptoms. The goal is to offer access t…
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Blood test revolution: pinpointing the cause of swelling attacks
Diagnosis Recruiting nowThis study evaluates whether new blood tests can more accurately diagnose the cause of recurrent angioedema—a condition causing severe swelling—compared to current tests. Researchers will compare novel diagnostic assays with traditional ones in 600 people aged 12 and older who ha…
Sponsor: Foundation For Rare Disease Research • Aim: Diagnosis
Last updated Aug 26, 2026 00:00 UTC
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New drug aims to calm stubborn hives triggered by cold or scratching
Symptom relief Recruiting nowThis early-stage study tests a single dose of an experimental drug called GTX-B001 in healthy people and those with chronic inducible urticaria—a condition where cold or scratching causes painful hives. The main goal is to check safety and how the body handles the drug. About 72 …
Phase 1 • Sponsor: Granular Therapeutics Limited • Aim: Symptom relief
Last updated Sep 11, 2026 00:00 UTC
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Can a smartphone app ease the misery of eczema, psoriasis, and hives?
Symptom relief Recruiting nowThis study tests whether a mobile app that provides psychological tools can improve quality of life for people with eczema, psoriasis, or chronic hives. Participants use the app over 32 weeks to learn coping strategies and wellness tips. The goal is to see if this digital approac…
Sponsor: National University Hospital, Singapore • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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New pill could soothe stubborn hives when allergy meds fail
Symptom relief Recruiting nowThis study tests an experimental daily pill, ritlecitinib, for adults with chronic spontaneous urticaria (long-term itchy hives and swelling) that antihistamines don't fully control. About 200 participants will receive either 50 mg, 100 mg, or a placebo for 12 weeks, then all wil…
Phase 2 • Sponsor: Pfizer • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Massive study seeks genetic roots of allergies and immune problems
Knowledge-focused Recruiting nowThis study aims to find the genetic causes behind certain allergic and immune system disorders. Researchers will collect blood, saliva, and tissue samples from up to 10,000 people of all ages, along with some family members. No treatments are given; the goal is simply to learn mo…
Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC