Urinary system disorder
MONDO:0002118A disease involving the renal system.
Also known as: disease of renal system, disease or disorder of renal system, disease, urinary tract, disease, urologic, disease, urological, diseases, urinary tract, diseases, urologic, diseases, urological
5523 clinical trials for this condition and its sub-types, 72 tagged with Urinary system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Urinary system disorder
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Kidney disorder 223 trials · 4,032 incl. sub-types
57 sub-types
- Chronic kidney disease 1,091 trials · 1,566 incl. sub-types Sub-types →
- Kidney failure 236 trials · 1,389 incl. sub-types Sub-types →
- Kidney neoplasm 59 trials · 860 incl. sub-types Sub-types →
- Nephritis 16 trials · 503 incl. sub-types Sub-types →
- Glomerular disorder 9 trials · 481 incl. sub-types Sub-types →
- Inherited kidney disorder 1 trial · 317 incl. sub-types Sub-types →
- Nephrolithiasis 252 trials · 254 incl. sub-types Sub-types →
- Proteinuria 65 trials · 137 incl. sub-types Sub-types →
- Impaired renal function disease 109 trials · 129 incl. sub-types Sub-types →
- Cystic kidney disease 8 trials · 87 incl. sub-types Sub-types →
- Nephrosis 0 trials · 71 incl. sub-types Sub-types →
- Renal infectious disease 16 trials · 64 incl. sub-types Sub-types →
- Renal tubule disorder 1 trial · 47 incl. sub-types Sub-types →
- Diabetes insipidus 33 trials · 37 incl. sub-types Sub-types →
- Renal tubular transport disease 0 trials · 17 incl. sub-types Sub-types →
- Hydronephrosis 7 trials · 9 incl. sub-types Sub-types →
- Stricture or kinking of ureter 9 trials
- Hypertensive nephropathy 8 trials Sub-types →
- Nephrocalcinosis 7 trials · 8 incl. sub-types Sub-types →
- Renal artery disease 3 trials · 7 incl. sub-types Sub-types →
- Fetal lower urinary tract obstruction 0 trials · 6 incl. sub-types Sub-types →
- Congenital primary megaureter 5 trials Sub-types →
- Renal hypertension 0 trials · 4 incl. sub-types Sub-types →
- Distal renal tubular acidosis 3 trials Sub-types →
- Exstrophy-epispadias complex 1 trial · 3 incl. sub-types Sub-types →
- Acute tubulointerstitial nephritis 2 trials
- Kidney cortex necrosis 2 trials
- IgG4-related kidney disease 1 trial
- Anuria 1 trial
- Crush syndrome 1 trial
- Obstructive nephropathy 1 trial
- Orthostatic proteinuria 1 trial
- Renal hypoplasia 1 trial Sub-types →
- Renal nutcracker syndrome 1 trial
- Arnold stickler bourne syndrome 0 trials
- C1q nephropathy 0 trials
- X-linked diffuse leiomyomatosis-Alport syndrome 0 trials Sub-types →
- Atheroembolism of kidney 0 trials
- Atypical Fanconi syndrome-neonatal hyperinsulinism syndrome 0 trials
- Autosomal dominant progressive nephropathy with hypertension 0 trials
- Congenital megacalycosis 0 trials Sub-types →
- Congenital renal artery stenosis 0 trials
- Duplication of urethra 0 trials
- Idiopathic non-lupus full-house nephropathy 0 trials
- Kidney cortex disease 0 trials
- Kidney hypertrophy 0 trials
- Kidney papillary necrosis 0 trials Sub-types →
- Lachiewicz sibley syndrome 0 trials
- Neonatal renal venous thrombosis 0 trials
- Non-syndromic supernumerary kidneys 0 trials
- Oligomeganephronia 0 trials
- Perinephritis 0 trials
- Pyonephrosis 0 trials
- Renal aminoaciduria 0 trials
- Renal dysplasia 0 trials Sub-types →
- Renal tubular dysgenesis 0 trials Sub-types →
- Tubulointerstitial nephritis and uveitis syndrome 0 trials
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Urinary system neoplasm 21 trials · 1,690 incl. sub-types
8 sub-types
- Malignant urinary system neoplasm 75 trials · 1,664 incl. sub-types Sub-types →
- Kidney neoplasm 59 trials · 860 incl. sub-types Sub-types →
- Urinary bladder neoplasm 65 trials · 699 incl. sub-types Sub-types →
- Urothelial neoplasm 2 trials · 693 incl. sub-types Sub-types →
- Benign urinary system neoplasm 50 trials · 62 incl. sub-types Sub-types →
- Ureter neoplasm 2 trials · 34 incl. sub-types Sub-types →
- Urethra neoplasm 3 trials · 31 incl. sub-types Sub-types →
- Prostate phyllodes tumor 0 trials Sub-types →
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Urinary bladder disorder 24 trials · 1,152 incl. sub-types
17 sub-types
- Urinary bladder neoplasm 65 trials · 699 incl. sub-types Sub-types →
- Overactive bladder 168 trials
- Female stress incontinence 137 trials
- Cystitis 12 trials · 72 incl. sub-types Sub-types →
- Ureterolithiasis 49 trials
- Bladder neck obstruction 12 trials
- Hinman syndrome 5 trials
- Bladder calculus 5 trials Sub-types →
- Vesicoureteral reflux 5 trials Sub-types →
- Detrusor sphincter dyssynergia 3 trials
- Urinary schistosomiasis 3 trials
- Low compliance bladder 2 trials
- Postcholecystectomy syndrome 1 trial
- Bladder diverticulum 0 trials Sub-types →
- Disorder of neck of urinary bladder 0 trials Sub-types →
- Ureterocele 0 trials
- Urinary bladder tuberculosis 0 trials
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Urolithiasis 119 trials · 312 incl. sub-types
2 sub-types
- Nephrolithiasis 252 trials · 254 incl. sub-types Sub-types →
- Lower urinary tract calculus 0 trials · 5 incl. sub-types Sub-types →
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Urinary tract infection 156 trials · 250 incl. sub-types
5 sub-types
- Bacterial urinary tract infection 55 trials · 81 incl. sub-types Sub-types →
- Renal infectious disease 16 trials · 64 incl. sub-types Sub-types →
- Trichomonas vaginitis urogenital infection 7 trials Sub-types →
- Urinary schistosomiasis 3 trials
- Pyoureter 0 trials
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Ureteral disorder 2 trials · 95 incl. sub-types
8 sub-types
- Ureterolithiasis 49 trials
- Ureter neoplasm 2 trials · 34 incl. sub-types Sub-types →
- Ureteral obstruction 9 trials
- Vesicoureteral reflux 5 trials Sub-types →
- Pyoureter 0 trials
- Ureter tuberculosis 0 trials
- Ureteritis 0 trials
- Ureterocele 0 trials
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Urethral disorder 1 trial · 70 incl. sub-types
10 sub-types
- Urethra neoplasm 3 trials · 31 incl. sub-types Sub-types →
- Urethral obstruction 3 trials · 26 incl. sub-types Sub-types →
- Urethritis 5 trials · 6 incl. sub-types Sub-types →
- Urethral syndrome 4 trials
- Urethral intrinsic sphincter deficiency 3 trials
- Fibroepithelial polyp of urethra 0 trials
- Prolapse of urethra 0 trials
- Urethral calculus 0 trials
- Urethral false passage 0 trials
- Urethral gland abscess 0 trials
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Urinary tract obstruction 12 trials · 27 incl. sub-types
2 sub-types
- Hydronephrosis 7 trials · 9 incl. sub-types Sub-types →
- Ureteral obstruction 9 trials
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Bacteriuria 11 trials
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Idiopathic hypercalciuria 3 trials
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Paraneoplastic renal syndrome 0 trials · 3 incl. sub-types
1 sub-type
- Oncogenic osteomalacia 3 trials
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Congenital urachal anomaly 0 trials
4 sub-types
- Patent urachus 0 trials
- Urachal cyst 0 trials
- Urachal diverticulum 0 trials
- Urachal sinus 0 trials
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Hypercalciuria, absorptive, 1 0 trials
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Hypercalciuria, absorptive, 2 0 trials
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Hyperglycinuria 0 trials
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Megacystis-megaureter syndrome 0 trials
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Meningitis-retention syndrome 0 trials
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Postorgasmic illness syndrome 0 trials
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Pyuria 0 trials
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Urothelial hyperplasia 0 trials
2 sub-types
- Flat urothelial hyperplasia 0 trials
- Papillary urothelial hyperplasia 0 trials
Most studied deeper sub-types
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Atacicept's Long-Term promise for kidney disease
Disease control By invitation onlyThis study looks at the long-term safety and effects of atacicept in people with IgA nephropathy, a kidney disease. Participants have already completed a previous trial with atacicept. Researchers will monitor side effects and measure kidney function over time to see if the drug …
Phase 2 • Sponsor: Vera Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New drug aims to slow kidney failure in common kidney disease
Disease control OngoingThis phase 3 trial tests whether the drug atrasentan can slow kidney function loss in people with IgA nephropathy, a disease that can lead to kidney failure. About 404 participants receive either atrasentan or a placebo, along with standard care. The main goal is to see if atrase…
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Could a testosterone shot before surgery speed recovery?
Disease control OngoingThis early-phase trial is testing whether giving testosterone replacement therapy to men with low testosterone before and after major urologic surgery is safe and might improve recovery. Researchers will track quality of life, frailty, complications, hospital stay length, and rea…
Phase 1 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New shot shows promise in slowing kidney disease
Disease control OngoingThis phase 3 study tests BION-1301 (Zigakibart) in 383 adults with IgA nephropathy, a kidney disease that can lead to kidney failure. Participants receive either the drug or a placebo as a shot every 2 weeks for 2 years. The main goal is to see if the drug helps preserve kidney f…
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Bringing the hospital to your living room: a massive study tests home care for common illnesses
Disease control By invitation onlyThis study looks at whether treating patients at home for conditions like infections, heart failure, diabetes, and COPD can lead to better health outcomes and satisfaction compared to traditional hospital stays. Nearly 10,000 adults will receive hospital-level care at home, inclu…
Sponsor: OSF Healthcare System • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Cell therapy aims to fix stubborn bladder leaks after failed surgery
Disease control OngoingThis study tests a new treatment called AMDC-USR (iltamiocel) for women who still have stress urinary incontinence after having surgery for it. The treatment uses the patient's own muscle cells injected into the urinary sphincter to strengthen it. Half of the 96 participants get …
Phase 3 • Sponsor: Cook MyoSite • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Implantable nerve stimulator shows promise for bladder control
Disease control OngoingThis study tests a small implant called INTIBIA that stimulates a nerve in the leg to help control sudden, strong urges to urinate. About 208 adults with overactive bladder and frequent leaking episodes will receive the implant. The goal is to see if it safely reduces leaking by …
Sponsor: Coloplast A/S • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Bladder cancer patients who Can't take chemo may get new option
Disease control OngoingThis phase II trial tests a combination of an immunotherapy drug called sasanlimab and focused radiation given before bladder removal surgery in 33 patients with muscle-invasive bladder cancer who cannot take standard chemotherapy. The goal is to see if this approach is safe, fea…
Phase 2 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Home urine tests may let men skip clinic visits for prostate symptoms
Knowledge-focused PausedThis study compares at-home urinary testing devices with standard clinic tests for men who have lower urinary tract symptoms due to an enlarged prostate. Participants either use the devices at home or come to the clinic for the same measurements, including urine flow, bladder emp…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
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No more catheters? new device aims to make bladder testing easier
Knowledge-focused OngoingThis study is testing a new wireless device called the Glean Urodynamics System (GUS) that monitors bladder pressure without a catheter. It involves 28 adult women with urinary symptoms. Participants will use the device during standard tests and at home. The goal is to see if GUS…
Sponsor: Bright Uro • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Major study aims to settle debate on best bladder cancer treatment
Knowledge-focused OngoingThis study compares two common treatments for recurrent non-muscle-invasive bladder cancer: medical therapy (drugs placed in the bladder) and surgery (bladder removal). Researchers will track quality of life and patient experiences in 570 adults to see which approach works better…
Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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AI overlays put to the test in robotic surgery: will they help or hinder surgeons?
Knowledge-focused OngoingThis study looks at whether adding AI-powered images to the surgeon's screen during single-port robotic surgery makes the surgeon's job easier or harder. About 90 urology surgeons and residents will fill out a questionnaire after surgery to rate their mental workload. The goal is…
Sponsor: University of Illinois at Chicago • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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New registry tracks how bladder testing device works in real life
Knowledge-focused OngoingThis study is a registry that gathers information from medical records of 500 adults who had a bladder function test using the Glean Urodynamics System. The goal is to see how the system is used in everyday medical practice. No new treatments or procedures are given; it simply co…
Sponsor: Bright Uro • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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New digital tool aims to cut medical errors during hospital transfers
Knowledge-focused By invitation onlyThis study tests a new digital platform that helps doctors and nurses share important patient information when a person is moved from one hospital to another. About 1,000 adults being transferred to a major hospital will take part. The goal is to see if better information sharing…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC