Ulcer of lower limbs
MONDO:0004601Ulcer of lower limbs is a chronic ulcer of skin where the ulcer is not a decubitus ulcer.
Also known as: Ulcer of ankle, Ulcer of calf, Ulcer of heel and midfoot, Ulcer of thigh
144 clinical trials for this condition and its sub-types, 124 tagged with Ulcer of lower limbs itself.
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Amniotic membrane wrap studied for stubborn leg sores in seniors
Disease control Stopped earlyThis study tested a special wrap made from donated placenta tissue (human amniotic membrane) to help heal difficult leg ulcers caused by poor blood flow in people aged 65 and older. The goal was to see if the wrap could close the wound completely within 12 weeks. The trial was st…
Sponsor: BioLab Holdings • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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New synthetic skin patch tested for Hard-to-Heal wounds
Disease control Stopped earlyThis study tested a man-made skin substitute called Restrata for treating diabetic foot ulcers and venous leg ulcers. For diabetic foot ulcers, Restrata was compared to standard wound care. For venous leg ulcers, it was compared to a living cell-based skin substitute (Apligraf). …
Sponsor: Acera Surgical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New wound pump shows promise for stubborn leg ulcers
Symptom relief Stopped earlyThis study tested whether a single-use negative pressure wound therapy system (PICO) helps heal hard-to-treat venous leg ulcers better than standard care. About 142 adults with leg ulcers that had lasted at least 6 weeks took part. The main goal was to see if more ulcers healed c…
Sponsor: Smith & Nephew, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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New tool aims to spot wound healing hurdles early
Knowledge-focused Stopped earlyThis study is for people with wounds that have developed hypergranulation (overgrown tissue that slows healing). Researchers will take photos and use a new assessment tool to grade the severity. About 100 adults and children in the UK will take part. The goal is to create a stand…
Sponsor: Ennogen Healthcare Limited • Aim: Knowledge-focused
Last updated Aug 20, 2026 00:00 UTC