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Trisomy 21

MONDO:0700126

A chromosomal disorder consisting of the presence of an extra chromosome 21.

12 clinical trials for this condition and its sub-types, 9 tagged with Trisomy 21 itself.

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Where it sits in the disease tree

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Part of

↑ Down syndrome (138) ↑ Trisomy (24)

Sub-types of Trisomy 21

Mosaic trisomy 21 1 trial
Complete trisomy 21 0 trials

Including sub-types (12) Tagged with Trisomy 21 (9)

Trials to join now! 5 Not yet recruiting 1 Not yet finished but already full! 2 Completed 4

Playtime as brain training: a new approach targets thinking skills in down syndrome

Disease control Not yet recruiting

This trial tests a play-based program called EXPO, where caregivers guide children with Down syndrome through fun activities designed to strengthen executive function, the mental skills behind planning, focus, and self-control. Researchers will compare children who receive EXPO r…

Sponsor: Colorado State University • Aim: Disease control

Last updated Aug 30, 2026 00:00 UTC