Toxic maculopathy due to antimalarial drugs
MONDO:0017204Toxic maculopathy due to antimalarial drugs is a rare, acquired eye disease, due to long-term exposure to chloroquinine (CQ) or hydrochloroquinine (HCQ), characterized by a slowly progressive, usually non-reversible, development of bilateral atrophic bull's-eye maculopathy (progressive loss of central vision acuity, reduced color vision and central scotoma), which in severe cases can spread over the entire fundus, leading to widespread retinal atrophy and visual loss.
3 clinical trials for this condition and its sub-types, 3 tagged with Toxic maculopathy due to antimalarial drugs itself.
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Can your genes predict eye damage from a common arthritis drug?
Knowledge-focused Recruiting nowThis study looks at whether certain genes make some people more likely to develop eye damage from the drug Plaquenil, which is used for autoimmune diseases like lupus and rheumatoid arthritis. Researchers will compare people who have had eye damage from Plaquenil with those who h…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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New eye scans could revolutionize how we see retinal disease
Knowledge-focused Recruiting nowThis study uses special cameras to take ultra-detailed pictures of the back of the eye in people with retinal diseases like macular degeneration and retinitis pigmentosa. Researchers aim to develop new ways to diagnose and track these conditions by measuring cell density and func…
Sponsor: Food and Drug Administration (FDA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC