Torsades de pointes
MONDO:0005478A malignant form of polymorphic ventricular tachycardia that is characterized by heart rate between 200 and 250 beats per minute, and qrs complexes with changing amplitude and twisting of the points. The term also describes the syndrome of tachycardia with prolonged ventricular repolarization, long qt intervals exceeding 500 milliseconds or bradycardia. Torsades de pointes may be self-limited or may progress to ventricular fibrillation.
33 clinical trials for this condition and its sub-types, 4 tagged with Torsades de pointes itself.
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Millions of drug alerts may be misleading: massive study to find out which QT drugs actually harm hearts
Knowledge-focused Recruiting nowThis study looks at whether certain medications known to affect the heart's electrical activity (QT-prolonging drugs) actually cause major heart problems in hospitalized adults. Researchers will analyze data from over 990,000 patients across Ontario hospitals, comparing those who…
Sponsor: St. Joseph's Healthcare Hamilton • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Can a patch catch hidden heart risks better than standard ECGs?
Knowledge-focused Recruiting nowThis study compares a continuous heart-monitoring patch with standard electrocardiograms (ECGs) in 60 adults receiving cancer drugs that can cause dangerous heart rhythm changes. The goal is to see if the patch detects problems more accurately and consistently. Participants will …
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Early menopause heart risk under microscope: hormone Therapy's role questioned
Knowledge-focused Recruiting nowThis study looks at how early menopause (premature ovarian insufficiency) affects the heart's electrical signals, which can raise the risk of dangerous heart rhythms. Researchers will compare 120 women with and without this condition, and also check how hormone replacement therap…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC