TNF receptor 1-associated periodic fever syndrome
MONDO:0007727A periodic fever syndrome, characterized by recurrent fever, arthralgia, myalgia and tender skin lesions lasting for 1 to 3 weeks, associated with skin, joint, ocular and serosal inflammation and complicated by secondary amyloidosis.
Also known as: autosomal dominant familial periodic fever, FHF, Hibernian fever, familial, TNF receptor 1-associated periodic fever syndrome, TNF receptor 1-associated periodic syndrome, TNF receptor-associated periodic syndrome, TRAPS, TRAPS syndrome
14 clinical trials for this condition and its sub-types, 4 tagged with TNF receptor 1-associated periodic fever syndrome itself.
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Real-world check: does ilaris work safely for rare fever diseases?
Disease control Recruiting nowThis study watches children and adults who are already taking or about to start Ilaris for hereditary periodic fever syndromes or systemic juvenile idiopathic arthritis. Researchers will track side effects and how well the drug controls symptoms over 16 weeks. No new medicine is …
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Scientists seek genetic clues to mysterious fever diseases
Knowledge-focused Recruiting nowThis study aims to learn more about the genetics and natural history of autoinflammatory diseases, which cause repeated fevers and inflammation. Researchers will study up to 5,000 people, including patients, their relatives, and healthy volunteers. Participants provide blood and …
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Sep 11, 2026 00:00 UTC
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Scientists hunt for genetic clues in rare childhood immune disorders
Knowledge-focused Recruiting nowThis study is not a treatment trial. It aims to collect blood samples from 400 children and their relatives who have rare autoimmune or autoinflammatory diseases (like lupus or juvenile arthritis). Researchers will analyze the samples to find genetic mutations that cause these co…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC