Synucleinopathy
MONDO:0000510A neurodegenerative disease that is characterized by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibers or glial cells. [url:http://en.wikipedia.org/wiki/Synucleinopathies ]
Also known as: alpha synucleinopathies, synucleinopathies
237 clinical trials for this condition and its sub-types, 18 tagged with Synucleinopathy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Synucleinopathy
-
Lewy body dementia 130 trials
-
Multiple system atrophy 110 trials · 119 incl. sub-types
4 sub-types
- Pure autonomic failure 18 trials
- Multiple system atrophy, parkinsonian type 12 trials
- Multiple system atrophy, cerebellar type 3 trials
- Striatonigral degeneration 0 trials Sub-types →
Most studied deeper sub-types
-
Brain scan breakthrough: new tracer could catch Parkinson's early
Diagnosis CompletedThis completed study tested a new radioactive tracer called [18F] - FD17 for PET imaging to detect clumps of a protein called alpha-synuclein in the brain. These clumps are linked to Parkinson's disease, multiple system atrophy, and a sleep disorder that often precedes Parkinson'…
Sponsor: Ruijin Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 09:11 UTC
-
Super MRI reveals hidden brain clues for Parkinson's risk
Knowledge-focused CompletedThis study used a very powerful 7 Tesla MRI to look for tiny brain changes in 15 people with idiopathic REM sleep behavior disorder (iRBD) compared to 15 healthy volunteers. iRBD is a sleep condition that often leads to Parkinson's disease years later. The goal was to find early …
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC