Squamous cell lung carcinoma
MONDO:0005097A carcinoma arising from squamous bronchial epithelial cells. It may be keratinizing or non-keratinizing. Keratinizing squamous cell carcinoma is characterized by the presence of keratinization, pearl formation, and/or intercellular bridges. Non-keratinizing squamous cell carcinoma is characterized by the absence of keratinization, pearl formation, and intercellular bridges. Cigarette smoking and arsenic exposure are strongly associated with squamous cell lung carcinoma.
Also known as: epidermoid cell carcinoma of lung, epidermoid cell carcinoma of the lung, epidermoid cell lung carcinoma, lung squamous cell carcinoma, squamous cell carcinoma of lung, squamous cell carcinoma of the lung, squamous cell lung cancer, squamous cell lung carcinoma
2924 clinical trials for this condition and its sub-types, 65 tagged with Squamous cell lung carcinoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Squamous cell lung carcinoma
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Non-small cell squamous lung carcinoma 83 trials · 88 incl. sub-types
1 sub-type
- Adenosquamous lung carcinoma 5 trials
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Lung occult squamous cell carcinoma 0 trials
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Experimental immune cell therapy targets Hard-to-Treat cancers
Disease control Stopped earlyThis early-phase trial tested a personalized cell therapy called ITIL-306 in people with advanced ovarian, lung, or kidney cancers that had not responded to standard treatments. The therapy uses a patient's own immune cells (TILs) taken from their tumor, modified to better attack…
Phase 1 • Sponsor: Instil Bio • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Cancer-Fighting super cells tested in solid tumors – study halted early
Disease control Stopped earlyThis study tested a personalized treatment where a patient's own immune cells were modified in a lab to recognize and attack unique markers on their cancer cells. It involved 8 people with advanced solid tumors like lung, pancreatic, or ovarian cancer that had not responded to st…
Phase 1/2 • Sponsor: Alaunos Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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A new approach to help homeless youth kick the habit?
Knowledge-focused Stopped earlyThis study aims to develop a smoking cessation program specifically designed for homeless youth. Researchers will interview and survey participants to understand their motivations for smoking and quitting. The goal is to build a program that addresses the unique challenges these …
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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Could a genetic marker guide future cancer therapies in taiwan?
Knowledge-focused Stopped earlyThis study is measuring how often a specific genetic marker (HLA-A*02:01) and a cancer-related protein (NY-ESO-1) appear in Taiwanese patients with solid tumors like head and neck, liver, lung, breast, and esophageal cancers. By understanding these frequencies, researchers hope t…
Sponsor: PharmaEssentia • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC
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New program aims to help pregnant smokers quit for healthier babies
Knowledge-focused Stopped earlyThis study aimed to help low-income pregnant women stop smoking and make their homes smoke-free. Smoking during pregnancy raises the risk of cancer and can lead to low birth weight and other health problems for the baby. The program offered support and referrals to services durin…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Lung cancer video trial fails to reach goal
Knowledge-focused Stopped earlyThis study aimed to see if a culturally tailored educational video could help African American, Korean, and Chinese adults learn about lung cancer and screening. Researchers planned focus groups and interviews with 11 participants to understand barriers. The trial was terminated …
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Lung cancer biomarker study halted after enrolling only 22 patients
Knowledge-focused Stopped earlyThis study aimed to find genetic changes in lung tissue and blood that could predict how squamous cell lung cancer progresses. Researchers planned to collect samples from 200 patients undergoing lung procedures, but the study was stopped early with only 22 participants. No treatm…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC