Spinocerebellar ataxia type 2
MONDO:0008458A subtype of type I autosomal dominant cerebellar ataxia (ADCA type I) characterized by truncal ataxia, dysarthria, slowed saccades and less commonly ophthalmoparesis and chorea.
Also known as: ATXN2 autosomal dominant cerebellar ataxia type I, OPCA2, SCA2, autosomal dominant cerebellar ataxia type I caused by mutation in ATXN2, spinocerebellar ataxia type 2, ALS13, SCA 2, Wadia swami syndrome
38 clinical trials for this condition and its sub-types, 10 tagged with Spinocerebellar ataxia type 2 itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
Sub-types of Spinocerebellar ataxia type 2
-
Hope for ataxia: experimental drug shows promise in Late-Stage trial
Disease control CompletedThis study tested a drug called troriluzole in 141 adults with spinocerebellar ataxia, a rare disease that affects balance and coordination. Participants took either the drug or a placebo daily for 8 weeks. The main goal was to see if troriluzole could improve symptoms like walki…
Phase 2/3 • Sponsor: Biohaven Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
-
New blood test could replace risky prenatal procedures for genetic diseases
Diagnosis CompletedThis study aimed to develop a non-invasive prenatal test using fetal cells from a mother's blood to detect triplet repeat diseases like Huntington's disease, Fragile X syndrome, and certain types of muscular dystrophy and ataxia. Researchers enrolled 60 pregnant women at risk and…
Sponsor: University Hospital, Montpellier • Aim: Diagnosis
Last updated Jun 27, 2026 07:53 UTC
-
Hunting for the first clues of a devastating brain disease
Knowledge-focused CompletedThis study follows people who have a 50% chance of inheriting a gene for spinocerebellar ataxia, a group of progressive brain disorders that affect movement and coordination. The goal is to identify the earliest clinical signs and biological markers that appear before the disease…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
-
Brain scan and spinal tap study aims to speed up ataxia drug trials
Knowledge-focused CompletedThis completed study looked at 40 people with spinocerebellar ataxia types 2 and 7, a rare brain disease that affects movement. Researchers used MRI scans and lumbar punctures over one year to track changes in the brain and body. The goal was to find reliable markers that could b…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC