Spinal muscular atrophy, type IV
MONDO:0010056Proximal spinal muscular atrophy type 4 (SMA4) is the adult-onset form of proximal spinal muscular atrophy characterized by muscle weakness and hypotonia resulting from the degeneration and loss of the lower motor neurons in the spinal cord and the brain stem nuclei.
Also known as: SMA type 4, SMA type IV, SMA-IV, SMA4, spinal muscular atrophy of adults, spinal muscular atrophy, adult form, spinal muscular atrophy, type IV, spinal muscular atrophy-4
17 clinical trials for this condition and its sub-types, 2 tagged with Spinal muscular atrophy, type IV itself.
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Laser test could objectively measure nerve pain for first time
Diagnosis CompletedThis study tested whether a diode laser can act as a biomarker to measure neuropathic pain in people with peripheral neuropathy. Researchers compared pain responses to a lidocaine patch versus a placebo patch in 75 participants. The goal was to see if the laser test could disting…
Sponsor: University of Utah • Aim: Diagnosis
Last updated Jun 27, 2026 12:09 UTC
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Spinal zap trial aims to help SMA patients move better
Symptom relief CompletedThis small pilot study tested whether a temporary spinal cord stimulator (like a pacemaker for the spine) could help people with spinal muscular atrophy types 3 and 4 move their legs better. Three adults who could stand independently received the implant for up to 29 days. The go…
Sponsor: Marco Capogrosso • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC