Spinal fracture

This study tests a new device called VCFix for treating a broken bone in the spine (vertebral compression fracture). Ten adults with a single recent fracture will receive the implant to see if the procedure is safe and works as intended. The goal is to gather early data to plan a…

This study tests a device called AGN1 LOEP SV Kit for people with painful spinal fractures caused by osteoporosis. The device is injected into the broken vertebra to stabilize it. Researchers will track pain relief over 12 months in 100 participants aged 50 and older.

This study compares a new device (AGN1 LOEP) to standard bone cement for treating painful spine fractures caused by osteoporosis. The new device is injected into the broken vertebra, where it hardens and then slowly gets replaced by new bone. The trial involves 408 adults aged 50…

This study is testing a bone graft implant called OsteoPearl in 25 adults aged 50 and older who have a spinal compression fracture. The implant is placed during a standard procedure to stabilize the fracture. Researchers will track pain and quality of life over 30 days to see if …

This study compares two bone cements used to treat painful spinal fractures caused by osteoporosis. One cement includes a softener (V-Flex) to make it less rigid, while the other is standard cement (V-Steady). The goal is to see if the softer cement reduces the chance of new frac…

This study looks at people with a single broken bone in the middle-to-lower back (thoracolumbar burst fracture) but no nerve damage. It compares two standard treatments: surgery and non-surgical care (like a brace). The goal is to see which approach leads to better daily function…

This study tests a new ultrasound device that measures bone properties in the lower leg to predict fracture risk in adults over 55. It aims to see if it works as well as or better than standard DXA scans, without using radiation. Researchers will follow 1,600 participants for thr…

This study tests whether injecting bone cement into the spine can prevent fractures after high-dose radiation treatment for cancer that has spread to the backbone. About 87 patients with solid tumors and spinal metastases will receive either standard radiation alone or radiation …

This study tests whether a nerve block called erector spinae plane block can reduce the amount of morphine needed for pain after spinal fracture surgery. About 86 adults having minimally invasive spine surgery will be randomly assigned to receive either the nerve block or a place…

This study was designed to compare two procedures—vertebroplasty and kyphoplasty—for treating spinal fractures caused by trauma. Researchers planned to measure how much bone cement was injected and how well the spine's shape and function were restored. However, the study was with…

This study looks at three ways surgeons place screws in the spine during surgery: using a robot, using a navigation system, or doing it by hand. The goal is to see which method leads to fewer screws needing to be fixed in a second surgery within the first year. About 932 adults w…

This study looks back at medical records of 146 adults with stable spine fractures caused by falls or accidents. It compares three treatments: wearing a brace, a minimally invasive bone cement procedure, or spinal fusion surgery. The goal is to see which option leads to the best …

This study follows 150 adults undergoing back-of-the-neck and upper spine surgery with metal screws and rods (posterior fixation) for injuries, tumors, or worn-out discs. Researchers track complications, X-ray results, and patient-reported pain over time. The goal is to better un…