Spinal cord neoplasm

This phase 2 trial tests whether adding the targeted drug abemaciclib to standard chemotherapy (temozolomide) helps children and young adults with newly diagnosed high-grade glioma live longer without their cancer growing. About 45 participants will receive either the combination…

This study tests whether placing vancomycin powder directly into the wound during spine surgery can prevent infections in high-risk patients, such as those with spinal deformities or tumors. Half of the 76 adult participants will receive the powder, while the other half will not.…

This study tests a highly precise radiation system (CT-on-Rails or Trilogy) to treat spine tumors that have spread from other cancers. About 150 participants will receive three radiation sessions over two weeks. Researchers will track pain relief and side effects using patient qu…

This study is a registry that collects medical records, quality-of-life questionnaires, and tissue samples from 900 people with spine tumors or other spine disorders. The goal is to learn more about these conditions to guide better treatment in the future. Participants must be be…

This study was designed to test experimental nano-based painkillers on nerve cells taken from people having surgery for spinal tumors. The goal was to see how well these treatments might work for pain. However, the study was withdrawn before any participants were enrolled, so no …

This study looks at three ways surgeons place screws in the spine during surgery: using a robot, using a navigation system, or doing it by hand. The goal is to see which method leads to fewer screws needing to be fixed in a second surgery within the first year. About 932 adults w…

This study looks back at 50 people who had surgery for rare spinal cord tumors between 2022 and 2024. Researchers want to see how the surgery changed their nerve function, movement, and daily life. They also track complications like infections or bleeding. The goal is to learn wh…