Spermatogenic failure 3
MONDO:0011720Any azoospermia in which the cause of the disease is a mutation in the SLC26A8 gene.
Also known as: SLC26A8 azoospermia, azoospermia caused by mutation in SLC26A8, spermatogenic failure 3, spermatogenic failure type 3, SPGF3
12 clinical trials for this condition and its sub-types, 9 tagged with Spermatogenic failure 3 itself.
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Fertility drug trial for men with no sperm pulled before it began
Disease control CancelledThis study aimed to see if the drug clomiphene citrate could help men with a condition called non-obstructive azoospermia, where the body produces little to no sperm. The plan was to give the drug or a placebo for nine months, then check if sperm could be found in the semen or th…
Phase 3 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can acne drug or hormone shots help men with low sperm count?
Disease control By invitation onlyThis study tests two treatments—isotretinoin (an acne medication) and hCG (a hormone)—to see if they can help men with low or no sperm count produce moving sperm. About 100 men aged 19 to 50 will take one of the drugs for three months. The goal is to find new options for male inf…
Phase 2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Jun 27, 2026 12:10 UTC
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Frozen testicle tissue may help infertile men have kids
Disease control OngoingThis experimental study tests whether frozen-thawed testis tissue, when grafted under the skin, can produce sperm in men with infertility. Five men will receive their own stored tissue. The goal is to see if viable sperm can be retrieved, potentially offering a future fertility o…
Sponsor: Herlev and Gentofte Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Needle instead of scalpel: new sperm retrieval method tested
Disease control OngoingThis study tests a non-surgical method to collect sperm from men with a condition called azoospermia, where no sperm is found in the semen. Using ultrasound guidance, doctors flush and suction fluid from a part of the testicle to retrieve sperm. If successful, this could help inf…
Sponsor: University of Pittsburgh • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC