Spasmodic dystonia
MONDO:0000485A chronic voice disorder characterized by momentary periods of uncontrolled spasms of the muscles of the larynx.
Also known as: laryngeal dyskinesia, laryngeal dystonia, spasmodic dysphonia, spastic dysphonia, abductor spasmodic dysphonia, adductor spasmodic dysphonia, mixed spasmodic dysphonia (type)
56 clinical trials for this condition and its sub-types, 39 tagged with Spasmodic dystonia itself.
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Virtual reality could replace pills for pain during ENT procedures
Symptom relief Not yet recruitingThis study compares two types of virtual reality (VR) during common ear, nose, and throat (ENT) procedures. One group will watch calming scenery, while the other plays an interactive puzzle game. Researchers want to see which better reduces pain and anxiety. The study will includ…
Sponsor: Cedars-Sinai Medical Center • Aim: Symptom relief
Last updated Aug 19, 2026 00:00 UTC
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Could magnetic pulses to the brain ease a rare voice disorder?
Symptom relief Not yet recruitingThis study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can improve voice quality in people with laryngeal dystonia, a condition that causes involuntary muscle spasms in the voice box. Twenty adults with the c…
Sponsor: Universidade Federal de Pernambuco • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC
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Silent speech no more: new device reads muscle signals to restore voice
Symptom relief Not yet recruitingThis study tests a new device that uses muscle signals from the face and neck to recognize silent speech and turn it into voice. It is for adults who have lost their voice due to laryngectomy or severe voice problems. The goal is to see if the device can accurately identify words…
Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Could a sleep drug calm shaky voices? small study aims to find out.
Symptom relief Not yet recruitingThis early study tests whether a long-acting form of sodium oxybate (Lumryz) can improve voice symptoms in 8 adults with spasmodic dysphonia or voice tremor. Participants will take the drug and have their voice and brain activity measured. The goal is to see if the drug works and…
Phase 1 • Sponsor: Kristina Simonyan • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Can video calls fix your voice? new study tests remote therapy for seniors
Symptom relief Not yet recruitingThis study compares voice therapy delivered in-person versus via telehealth for adults aged 55 and older with age-related voice problems. Thirty participants will receive four sessions of PhoRTE® voice exercises either face-to-face or through video calls. Researchers will measure…
Sponsor: University of Southern California • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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A tiny touch test aims to map lost sensation in the throat
Knowledge-focused Not yet recruitingResearchers at the University of California, San Francisco are studying how well a calibrated touch device measures sensation in the larynx and throat. The study includes adults with larynx or throat disorders, including those whose condition followed radiation or other cancer tr…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Can ultrasound make throat procedures easier and safer?
Knowledge-focused Not yet recruitingThis pilot study will test whether using ultrasound during common office procedures for voice and swallowing problems is helpful and practical. Researchers will enroll 200 adults with conditions like chronic cough, vocal cord issues, or swallowing difficulties. They will measure …
Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC