Small intestine adenocarcinoma
MONDO:0003198An adenocarcinoma that arises from the small intestine. Histologic variants include mucinous adenocarcinoma and signet ring cell carcinoma.
Also known as: adenocarcinoma - small intest., adenocarcinoma of small bowel, adenocarcinoma of small intestine, adenocarcinoma of the small bowel, adenocarcinoma of the small intestine, small bowel adenocarcinoma, small intestinal adenocarcinoma, small intestine adenocarcinoma
2933 clinical trials for this condition and its sub-types, 18 tagged with Small intestine adenocarcinoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Small intestine adenocarcinoma
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Duodenal adenocarcinoma 9 trials · 44 incl. sub-types
1 sub-type
- Ampulla of vater adenocarcinoma 11 trials · 42 incl. sub-types Sub-types →
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Jejunal adenocarcinoma 0 trials
Most studied deeper sub-types
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Immunotherapy before surgery shows promise for certain cancers
Disease control OngoingThis study tests whether giving immunotherapy before surgery can help people with MSI/dMMR tumors. The goal is to shrink or eliminate the tumor before it is removed, potentially improving survival. The trial includes adults with localized, resectable cancers such as colorectal, g…
Phase 2 • Sponsor: Centre Leon Berard • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Immunotherapy duo takes on rare tumors
Disease control OngoingThis phase 2 trial is testing a combination of two immunotherapy drugs, nivolumab and ipilimumab, in 798 people with over 50 types of rare cancers. The goal is to see if these drugs can shrink tumors by helping the immune system attack cancer cells. Participants receive the drugs…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Poop pills plus immunotherapy: new hope for colorectal cancer patients?
Disease control OngoingThis pilot trial tests whether giving fecal microbiota transplants (FMT) along with re-introducing anti-PD-1 immunotherapy (pembrolizumab or nivolumab) can help control metastatic colorectal cancer in patients who previously did not respond to immunotherapy alone. The study enrol…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Can a vaccine stop GI cancers from returning?
Prevention PausedResearchers are testing an experimental vaccine called Ad5.F35-hGCC-PADRE in adults who have had surgery and standard treatment for gastrointestinal cancers, including pancreatic, colorectal, esophageal, gastric, and small bowel adenocarcinomas. The trial aims to find a safe dose…
Phase 2 • Sponsor: Thomas Jefferson University • Aim: Prevention
Last updated Sep 16, 2026 00:00 UTC