Singleton-Merten dysplasia

Singleton-Merten dysplasia is characterized by dental dysplasia, progressive calcification of the thoracic aorta with stenosis, osteoporosis and expansion of the marrow cavities in hand bones. Additional features included generalized muscle weakness and atrophy, and chronic psoriasiform skin eruptions. It has been reported in four unrelated patients (male and female) and in a family with multiple affected members (male).

Also known as: Merten-Singleton syndrome, Singleton Merten syndrome, Singleton-Merten syndrome, singleton Merten syndrome, SGMRT1, SM syndrome, syndrome of widened medullary cavities of the metacarpals and phalanges, aortic calcification and abnormal dentition, widened medullary cavities of bone, aortic calcification, abnormal dentition, and muscular weakness

13 clinical trials for this condition and its sub-types, 1 tagged with Singleton-Merten dysplasia itself.