Shiga toxin-associated hemolytic uremic syndrome

MONDO:0019536

A rare thrombotic microangiopathy characterized by mechanical hemolytic anemia, thrombocytopenia, and renal dysfunction that is usually associated with prodromal enteritis caused by Shigella dysentriae type 1 or E. Coli.

Also known as: D+HUS, STEC Hemolytic Uremic Syndrome, Shiga-like toxin-associated HUS, Sxt-HUS, hemolytic-uremic syndrome with diarrhea, hemolytic-uremic syndrome with diarrhoea, typical HUS, typical hemolytic-uremic syndrome

15 clinical trials for this condition and its sub-types, 2 tagged with Shiga toxin-associated hemolytic uremic syndrome itself.

Follow this condition to get notified about new trials

Where it sits in the disease tree

Browse by category →

Part of

↑ Hemolytic anemia (180) ↑ Infection-related hemolytic uremic syndrome (2)

Including sub-types (15) Tagged with Shiga toxin-associated hemolytic uremic syndrome (2)

Trials to join now! 1 Completed 1

Can a drug shorten dialysis for kids with a rare kidney disease?

Disease control Completed

This study tested whether the drug eculizumab (Soliris) can help children with a severe kidney condition called STEC-HUS recover faster. The trial gave 100 children either eculizumab or a placebo over several weeks. The main goal was to see if the drug reduces the number of days …

Phase 3 • Sponsor: University Hospital, Toulouse • Aim: Disease control

Last updated Jun 27, 2026 12:29 UTC

Shiga toxin-associated hemolytic uremic syndrome

Where it sits in the disease tree

Can a drug shorten dialysis for kids with a rare kidney disease?