Severe hemophilia B
MONDO:0015715Severe hemophilia B is a form of hemophilia B characterized by a large deficiency of factor IX leading to frequent spontaneous hemorrhage and abnormal bleeding as a result of minor injuries, or following surgery or tooth extraction.
Also known as: severe factor IX deficiency, severe haemophilia type B, severe hemophilia type B
22 clinical trials for this condition and its sub-types, 9 tagged with Severe hemophilia B itself.
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New daily injection could cut bleeding episodes in hemophilia
Disease control OngoingThis study tests a medicine called concizumab for people with hemophilia A or B who do not have inhibitors. The goal is to see if a daily shot under the skin can prevent bleeding episodes safely. About 156 participants, aged 12 and older, will either start concizumab right away o…
Phase 3 • Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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New shot could cut bleeding episodes in severe hemophilia
Disease control OngoingThis phase 3 trial tests fitusiran, an injectable drug, in 91 males aged 12 and older with severe hemophilia A or B, with or without inhibitors. Participants first receive standard care for 6 months, then switch to fitusiran for about 3 years. The goal is to see if fitusiran redu…
Phase 3 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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AI takes on blood clotting: can ChatGPT guide surgeons on bleeding?
Knowledge-focused CancelledThis study evaluates whether artificial intelligence models can accurately interpret ROTEM blood clotting tests and recommend treatments for coagulopathy. Researchers will compare AI decisions to those of a panel of clinical experts using data from adults undergoing elective card…
Sponsor: Ondokuz Mayıs University • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Massive hemophilia study aims to uncover hidden costs and care gaps in china
Knowledge-focused OngoingThis study is observing 500 male patients aged 12 and older with severe hemophilia A or B across China. Researchers are collecting data on treatment patterns, costs, and quality of life to understand the true burden of the disease. The goal is to identify gaps in care and help im…
Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC