Seasonal affective disorder
MONDO:0000694A syndrome characterized by depressions that recur annually at the same time each year, usually during the winter months. Other symptoms include anxiety, irritability, decreased energy, increased appetite (carbohydrate cravings), increased duration of sleep, and weight gain. sad (seasonal affective disorder) can be treated by daily exposure to bright artificial lights (phototherapy), during the season of recurrence.
Also known as: SADS, sad
56 clinical trials for this condition and its sub-types, 3 tagged with Seasonal affective disorder itself.
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Can a light device lift winter mood?
Symptom relief CancelledResearchers are testing whether a Joovv Mini infrared light device changes mood, sleep, and activity levels during winter months. Participants include US-based adults with a history of mental health issues such as depression who live in colder regions. They will use the device an…
Sponsor: ProofPilot • Aim: Symptom relief
Last updated Sep 19, 2026 00:00 UTC
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Can a personalized mix of nerve stimulation and therapy rewire the brain for better mental health?
Symptom relief OngoingResearchers are testing a personalized, non-drug treatment for adults with ongoing depression, anxiety, trauma-related symptoms, sleep problems, attention difficulties, or substance-use concerns. Instead of assigning treatment by diagnosis alone, the study selects approaches base…
Sponsor: Tactical Mind Research Coalition, Inc. • Aim: Symptom relief
Last updated Sep 18, 2026 00:00 UTC
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Can a video chat therapy reduce suicide risk? new study hopes to find out
Symptom relief OngoingThis pilot study tests whether a brief cognitive behavioral therapy delivered via video conference can help adults with mood disorders who are at high risk for suicide. Forty participants will either receive the video therapy plus usual care, or usual care alone. The study will m…
Sponsor: Hyung Keun Park • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Virtual reality headsets tested to soothe ECT jitters
Symptom relief By invitation onlyThis study tests whether using a virtual reality (VR) relaxation session can lower anxiety in people about to receive electroconvulsive therapy (ECT). Twenty adults already receiving ECT for depression will try VR relaxation, breathing exercises, or no extra relaxation. Researche…
Sponsor: Universitair Ziekenhuis Brussel • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can a brief online therapy ease anxiety and depression in kids? new study aims to find out.
Symptom relief By invitation onlyThis study tests a brief behavioral therapy program delivered via telehealth (STEP-UP) for children and teens aged 8 to 16 with anxiety or depression. Participants are recruited from community health centers and randomly assigned to either STEP-UP or a referral to local mental he…
Sponsor: San Diego State University • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Gut health for the mind: postbiotics tested as mood boosters
Symptom relief OngoingThis study tests whether taking postbiotics (a dietary supplement) for 8 weeks can reduce depressive symptoms and improve mood in Korean adults aged 19-39 with mild to moderate mood issues. Fifty-two participants will receive either postbiotics or a placebo, and their mood will b…
Sponsor: Hanyang University • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Does blue light calm the depressed brain? a scan study investigates
Knowledge-focused OngoingResearchers at the University of Pittsburgh are testing whether brief exposure to blue light, compared with red light, can stabilize emotional brain function in adolescents and young adults with depressive symptoms. Participants undergo brain scans while viewing light, complete a…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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Withdrawn study aimed to boost mental health in young south asian women
Knowledge-focused CancelledThis study aimed to develop and test a 12-week mental health program designed specifically for young South Asian women aged 16-24 with mood or anxiety disorders. The program was meant to address cultural and gender needs. However, the study was withdrawn before any participants w…
Sponsor: Centre for Addiction and Mental Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Scientists probe the Mind-Sleep connection with brain and heart scans
Knowledge-focused By invitation onlyThis study looks at how mood disorders and insomnia interact by monitoring heart and brain activity. Researchers will measure signals like heart rate variability and brain waves in 200 people, including healthy volunteers and those with mood or sleep issues. The goal is to unders…
Sponsor: Qilu Hospital of Shandong University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC