Scleroderma
MONDO:0019340Scleroderma is a rare autoimmune connective tissue disorder characterized by abnormal hardening of the skin and, sometimes, other organs. It is classified into two main forms: localized scleroderma and systemic sclerosis (SSc), the latter comprising three subsets; diffuse cutaneous SSc (dcSSc), limited cutaneous SSc (lcSSc) and limited SSc (lSSc).
Also known as: scleroderma, scleroderma (disease)
339 clinical trials for this condition and its sub-types, 47 tagged with Scleroderma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Scleroderma
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Systemic sclerosis 261 trials · 295 incl. sub-types
6 sub-types
- Diffuse scleroderma 82 trials
- Diffuse cutaneous systemic sclerosis 30 trials
- Pulmonary systemic sclerosis 27 trials
- Limited cutaneous systemic sclerosis 2 trials Sub-types →
- Limited systemic sclerosis 0 trials
- Scleroderma, familial progressive 0 trials
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Localized scleroderma 14 trials · 15 incl. sub-types
2 sub-types
- Linear scleroderma 1 trial
- Lipodermatosclerosis 1 trial
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Neonatal scleroderma 0 trials
Most studied deeper sub-types
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New mRNA shot aims to calm stubborn autoimmune diseases
Disease control Not yet recruitingThis early-phase study tests a new drug called WGb-0301 for people with autoimmune diseases (like lupus or autoimmune hepatitis) that haven't responded to standard treatments. The drug uses mRNA technology to target and clear certain immune cells (B cells) that are causing the di…
Early phase 1 • Sponsor: West China Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New study aims to catch silent lung threat in scleroderma
Diagnosis Not yet recruitingThis study will screen 35 adults with scleroderma for pulmonary hypertension using echocardiography. The goal is to see how often this serious lung condition occurs in these patients. The study is not yet recruiting.
Sponsor: Assiut University • Aim: Diagnosis
Last updated Jun 27, 2026 07:51 UTC