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Rickets
MONDO:0005520Bone softening and weakening usually caused by deficiency or impaired metabolism of vitamin D. Deficiency of calcium, magnesium, or phosphorus may also cause rickets. It predominantly affects children who suffer from severe malnutrition. It manifests with bone pain, fractures, muscle weakness, and skeletal deformities.
Also known as: rachitis, rickets, rickets (disease), vitamin D hydroxylation-deficient rickets, active rickets, hypovitaminosis D, nutritional rickets, vitamin D deficiency disease
41 clinical trials for this condition and its sub-types, 10 tagged with Rickets itself.
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Sub-types of Rickets
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Hypophosphatemic rickets 3 trials · 19 incl. sub-types
1 sub-type
- Hereditary hypophosphatemic rickets 1 trial · 18 incl. sub-types Sub-types →
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Renal osteodystrophy 12 trials
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Hypocalcemic rickets 0 trials · 3 incl. sub-types
2 sub-types
- Vitamin D-dependent rickets, type 1 0 trials · 3 incl. sub-types Sub-types →
- Vitamin D-dependent rickets, type 2 0 trials Sub-types →
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Vitamin D-dependent rickets 0 trials · 3 incl. sub-types
3 sub-types
- Vitamin D-dependent rickets, type 1 0 trials · 3 incl. sub-types Sub-types →
- Vitamin D-dependent rickets, type 2 0 trials Sub-types →
- Vitamin D-dependent rickets, type 3 0 trials
Most studied deeper sub-types
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Can a single dose of zoledronic acid safely treat bone loss in dialysis patients?
Disease control Not yet recruitingThis trial investigates how the drug zoledronic acid is processed in the body of people with chronic kidney disease who are on dialysis and also have osteoporosis. It aims to find the best dose—either 2.5 mg or 5 mg—given as a single intravenous injection during a dialysis sessio…
Phase 1 • Sponsor: University of Campinas, Brazil • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Can a cheap arthritis drug shield kidneys from heart and bone damage?
Disease control Not yet recruitingThis study tests whether a low dose of colchicine, a common anti-inflammatory drug, can slow down blood vessel hardening and bone problems in people with stage 3 chronic kidney disease. About 60 adults will take colchicine or receive usual care for 12 months. The goal is to see i…
Phase 2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Can a vitamin D2 blast speed up recovery in lymphoma patients?
Disease control Not yet recruitingThis study compares a high-intensity loading dose of vitamin D2 to standard weekly dosing in 52 patients with newly diagnosed aggressive non-Hodgkin lymphoma who are also receiving standard chemotherapy. The goal is to see if the high-dose approach normalizes vitamin D levels fas…
Sponsor: Phramongkutklao College of Medicine and Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:14 UTC
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Dental scans and AI could spot rare bone diseases faster
Knowledge-focused Not yet recruitingThis study will take 3D scans of the inside of the mouth from 240 people with rare bone or cartilage diseases and from healthy volunteers. Researchers will use shape analysis and artificial intelligence to see if these scans can help tell different diseases apart. The goal is to …
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC