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Rett syndrome
MONDO:0010726A severe neurodevelopmental disorder affecting the central nervous system.
Also known as: RTS, RTT, Rett syndrome, Rett syndrome, X-linked dominant, Rett syndrome, atypical, X-linked dominant, Rett syndrome, preserved speech variant, X-linked dominant, Rett’s disease, Rett syndrome, Zappella variant
32 clinical trials for this condition and its sub-types, 31 tagged with Rett syndrome itself.
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Low-THC cannabis extract tested against rett syndrome symptoms
Symptom relief CompletedResearchers are testing a full-spectrum medicinal cannabis extract called NTI164 in girls and young women with Rett syndrome, a rare genetic disorder that affects movement, speech, and behavior. The study includes 14 participants aged 5 to 20 who take the extract daily for 16 wee…
Phase 1/2 • Sponsor: Fenix Innovation Group • Aim: Symptom relief
Last updated Sep 11, 2026 00:00 UTC
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Could a ketamine drug ease rett syndrome?
Symptom relief CompletedThis early study tested esketamine, a form of ketamine, in 3 girls with Rett syndrome. The goal was to see if weekly infusions over five weeks could improve symptoms and be safe. The trial is complete, but with only 3 participants, it's too small to draw firm conclusions.
Early phase 1 • Sponsor: Children's Hospital of Fudan University • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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New parent support programme shows promise for families of children with complex needs
Symptom relief CompletedThis pilot study tested a community-based group programme called 'Encompass' for parents of children under 5 with complex neurodisability. Fifteen parents in East London attended ten group sessions over six months. The study aimed to see if the programme was feasible and acceptab…
Sponsor: City, University of London • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Rett syndrome bone mystery: study probes early osteoporosis
Knowledge-focused CompletedThis study looked at why girls with Rett syndrome often develop weak bones (osteoporosis) at a very young age. Researchers checked bone density, looked at medical history, and measured certain proteins in the blood. The goal was to find risk factors and understand the biological …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC