Retinoschisis
MONDO:0004579An inherited or acquired disorder characterized by splitting of the retina into two layers. It results in loss of vision.
19 clinical trials for this condition and its sub-types, 5 tagged with Retinoschisis itself.
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Sub-types of Retinoschisis
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X-linked retinoschisis 4 trials
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Retinoschisis of fovea 1 trial
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Bullous retinoschisis 0 trials
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Flat retinoschisis 0 trials
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Retinoschisis, autosomal dominant 0 trials
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Experimental gene injection aims to save sight in rare eye disease
Disease control CompletedThis early-phase trial tested a gene therapy called ZM-01 in 2 boys aged 3 to 18 with X-linked retinoschisis, a rare genetic eye condition that causes vision loss. Each boy received an injection of the therapy into one eye. The main goal was to check safety, but researchers also …
Early phase 1 • Sponsor: Zhongmou Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Scientists investigate rare eye disease that blinds young boys
Knowledge-focused CompletedThis study looks at X-linked juvenile retinoschisis (XLRS), a rare inherited eye disease that causes vision loss in young males. Researchers will examine 351 participants, including affected males and female carriers, using eye exams, retinal photos, and genetic tests. The goal i…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC