Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations
MONDO:0008641An inherited group of small vessel diseases comprised of cerebroretinal vasculopathy (CRV), hereditary vascular retinopathy (HRV) and hereditary endotheliopathy with retinopathy, nephropathy and stroke (HERNS); all exhibiting progressive visual impairment as well as variable cerebral dysfunction.
Also known as: RVCL, RVCL-S, hereditary vascular retinopathy, retinal vasculopathy and cerebral leukoencephalopathy, vasculopathy, retinal, with cerebral leukoencephalopathy and systemic manifestations, ADRVCL, CRV, HVR
45 clinical trials for this condition and its sub-types, 3 tagged with Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations itself.
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Hope for RVCL: experimental drug tested in tiny trial
Disease control CompletedThis phase 2 trial tested the drug crizanlizumab in 18 people with RVCL, a rare and fatal genetic condition that damages small blood vessels in the brain and eyes. There is currently no treatment for RVCL. The study measured changes in brain lesions on MRI scans to see if the dru…
Phase 2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Apple watches reveal surprising effects of air purifiers on your body
Knowledge-focused CompletedThis study tested whether using an indoor air purifier changes health measures like heart rate, sleep, and oxygen levels. 42 healthy adults wore Apple Watches while using a real or fake (sham) air purifier at home. The goal was to see if cleaner air makes a short-term difference …
Sponsor: New York University Abu Dhabi • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC