Reticulohistiocytic granuloma

MONDO:0002984

A rare cutaneous lesion composed of eosinophilic histiocytes, which are often multinucleated. The lesions are yellow-brown papules affecting any part of the body. Patients are usually adult men. The prognosis is excellent. -- 2003

Also known as: reticulohistiocytic granuloma (morphologic abnormality), solitary Reticulohistiocytoma, solitary reticulohistiocytoma, solitary histiocytoma, solitary reticulohistiocytosis

7 clinical trials for this condition and its sub-types, 0 tagged with Reticulohistiocytic granuloma itself.

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↑ Histiocytosis (74)

Including sub-types (7) Tagged with Reticulohistiocytic granuloma (0)

Trials to join now! 2 Not yet finished but already full! 4 Completed 1

New drug targets tough childhood cancers with genetic flaws

Disease control Completed

This phase 2 trial tested the drug samotolisib in 18 children and young adults with advanced solid tumors, non-Hodgkin lymphoma, or histiocytic disorders that had spread, returned, or stopped responding to treatment. Only patients whose tumors had specific mutations in the TSC or…

Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control

Last updated Jun 27, 2026 12:23 UTC

Reticulohistiocytic granuloma

Where it sits in the disease tree

New drug targets tough childhood cancers with genetic flaws