REM sleep behavior disorder
MONDO:0005937A disorder characterized by episodes of vigorous and often violent motor activity during rem sleep (sleep, rem). The affected individual may inflict self injury or harm others, and is difficult to awaken from this condition. Episodes are usually followed by a vivid recollection of a dream that is consistent with the aggressive behavior. This condition primarily affects adult males. (From Adams et al., Principles of Neurology, 6th ed, p393)
75 clinical trials for this condition and its sub-types, 48 tagged with REM sleep behavior disorder itself.
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Sub-types of REM sleep behavior disorder
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Rapid eye movement sleep disorder 4 trials
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Brain scan breakthrough: new tracer could catch Parkinson's early
Diagnosis CompletedThis completed study tested a new radioactive tracer called [18F] - FD17 for PET imaging to detect clumps of a protein called alpha-synuclein in the brain. These clumps are linked to Parkinson's disease, multiple system atrophy, and a sleep disorder that often precedes Parkinson'…
Sponsor: Ruijin Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 09:11 UTC
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Could your phone detect Parkinson's? new study tests remote monitoring and skin tests
Knowledge-focused CompletedThis completed study enrolled 230 people with Parkinson's disease, a related sleep disorder, and healthy volunteers. Participants used a smartphone app to track their movements daily and underwent brain scans. Some also gave skin biopsies to test for a protein linked to Parkinson…
Sponsor: Ronald Postuma • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Super MRI reveals hidden brain clues for Parkinson's risk
Knowledge-focused CompletedThis study used a very powerful 7 Tesla MRI to look for tiny brain changes in 15 people with idiopathic REM sleep behavior disorder (iRBD) compared to 15 healthy volunteers. iRBD is a sleep condition that often leads to Parkinson's disease years later. The goal was to find early …
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC