Rectal disorder
MONDO:0001593A disease that involves the rectum.
Also known as: disease of rectum, disease or disorder of rectum, disorder of rectum, rectal disorder, rectum disease, rectum disease or disorder
793 clinical trials for this condition and its sub-types, 22 tagged with Rectal disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Rectal disorder
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Rectal neoplasm 433 trials · 690 incl. sub-types
4 sub-types
- Rectal cancer 433 trials · 633 incl. sub-types Sub-types →
- Epithelial neoplasm of rectum 0 trials · 398 incl. sub-types Sub-types →
- Anus neoplasm 87 trials · 140 incl. sub-types Sub-types →
- Benign neoplasm of rectum 2 trials Sub-types →
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Anus disorder 3 trials · 171 incl. sub-types
7 sub-types
- Anus neoplasm 87 trials · 140 incl. sub-types Sub-types →
- Proctitis 2 trials · 21 incl. sub-types Sub-types →
- Imperforate anus 6 trials
- Levator syndrome 1 trial
- Anal polyp 0 trials Sub-types →
- Anal spasm 0 trials
- Anorectal stricture 0 trials
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Anal fistula 57 trials
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Rectal prolapse 6 trials
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Polyp of rectum 3 trials
2 sub-types
- Anal polyp 0 trials Sub-types →
- Rectal hyperplastic polyp 0 trials
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Ulcer of anus and rectum 0 trials
Most studied deeper sub-types
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New stapler aims to reduce leaks after colon surgery
Disease control Recruiting nowThis study is testing a new surgical stapler, called the Signia circular stapler, in people having left-sided colon, sigmoid, or rectal surgery. The goal is to see if it lowers the chance of a leak where the colon is reconnected. About 137 adults will take part, and the main focu…
Sponsor: Medtronic - MITG • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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New hope for colorectal cancer: experimental drug faces off against avastin
Disease control Recruiting nowThis Phase 3 trial is testing whether a new medicine called PF-08634404, combined with standard chemotherapy, works better than the current treatment Avastin plus chemo for people whose colorectal cancer has spread. About 800 participants who have not had prior treatment for meta…
Phase 3 • Sponsor: Pfizer • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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New combo treatment aims to ease hemorrhoid pain and bleeding
Disease control Recruiting nowThis study is testing a new way to treat moderate-to-severe hemorrhoids by combining a laser procedure with a stitch technique. About 100 adults will receive the treatment and be followed for a year. The goal is to see if it reduces pain, bleeding, and tissue prolapse better than…
Sponsor: National and Kapodistrian University of Athens • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Can we predict and treat cancer wasting better? a new study investigates
Knowledge-focused Recruiting nowThis study is looking at why some people with advanced cancer lose weight and muscle, a condition called cachexia. Researchers will follow 800 patients with advanced lung, pancreatic, or colorectal cancer to see if there are distinct subtypes of cachexia based on symptoms, biomar…
Sponsor: Kaiser Permanente • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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Scientists dive deep into gut tissue to unravel childhood IBD
Knowledge-focused Recruiting nowThis study collects tissue, blood, and stool samples from 200 children with inflammatory bowel disease (IBD) or other gut disorders. Researchers will use a cutting-edge technique called spatial transcriptomics to map gene activity directly inside gut tissue. The goal is to better…
Sponsor: Seattle Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New MRI method could prevent unnecessary treatment changes in rectal cancer patients
Knowledge-focused Recruiting nowThis study aims to improve how doctors tell the difference between real tumor growth and pseudoprogression (a harmless, temporary increase in tumor size) after immunotherapy for rectal cancer. Researchers will use multiple MRI scans and blood tests from 300 participants to build …
Sponsor: Peiyi Xie • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC