Rectal carcinoma
MONDO:0044937A malignant epithelial neoplasm that arises from the rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas.
Also known as: cancer of rectum, cancer of the rectum, rectal cancer, carcinoma of rectum, carcinoma of the rectum, rectal carcinoma, rectum carcinoma
3269 clinical trials for this condition and its sub-types, 54 tagged with Rectal carcinoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Rectal carcinoma
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Rectum adenocarcinoma 232 trials · 233 incl. sub-types
4 sub-types
- Anus adenocarcinoma 0 trials · 1 incl. sub-types Sub-types →
- Rectal signet ring cell adenocarcinoma 1 trial
- Rectum mucinous adenocarcinoma 1 trial Sub-types →
- Rectal medullary carcinoma 0 trials
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Anal carcinoma 85 trials · 129 incl. sub-types
4 sub-types
- Anal squamous cell carcinoma 40 trials · 49 incl. sub-types Sub-types →
- Anal canal carcinoma 4 trials · 34 incl. sub-types Sub-types →
- Anal margin carcinoma 1 trial · 6 incl. sub-types Sub-types →
- Anus adenocarcinoma 0 trials · 1 incl. sub-types Sub-types →
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Squamous cell carcinoma of rectum 8 trials · 53 incl. sub-types
3 sub-types
- Anal squamous cell carcinoma 40 trials · 49 incl. sub-types Sub-types →
- Rectal adenosquamous carcinoma 0 trials
- Rectal cloacogenic carcinoma 0 trials
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Rectum carcinoma in situ 1 trial · 13 incl. sub-types
1 sub-type
- Anal canal carcinoma in situ 12 trials
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Rectosigmoid carcinoma 5 trials
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Rectal sarcomatoid carcinoma 0 trials
Most studied deeper sub-types
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New cocktail shows promise against tough rectal tumors
Disease control CompletedThis completed study looked at whether adding an immune-boosting drug called thymalfasin to standard chemoradiotherapy and a PD-1 inhibitor could help shrink advanced rectal tumors before surgery. Researchers studied 47 patients with stage II/III mid-low rectal cancer. The main g…
Sponsor: Beijing Friendship Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New antibody combo shows promise against Hard-to-Treat colorectal cancer
Disease control CompletedThis phase II trial tested two different drug combinations in 240 people with advanced HER2-positive colorectal cancer that had spread and could not be removed by surgery. One group received the antibodies trastuzumab and pertuzumab, while the other received cetuximab (an antibod…
Phase 2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Can acupuncture and ice chips beat chemo nerve damage?
Symptom relief CompletedThis phase 2 trial looked at whether adding acupuncture and acupressure to oral cryotherapy (sucking on ice chips) can reduce nerve pain caused by oxaliplatin chemotherapy in people with gastrointestinal cancers. 78 patients were split into two groups: one got cryotherapy alone, …
Phase 2 • Sponsor: University of Washington • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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New MRI technique may spot complete cancer response without surgery
Knowledge-focused CompletedThis observational study looked at whether a special MRI measurement called T1 relaxation time can accurately detect scar tissue (fibrosis) that indicates a complete response to chemotherapy and radiation in people with locally advanced rectal cancer. 44 participants received sta…
Sponsor: Vejle Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC