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Raynaud disease
MONDO:0008364An episodic vasoconstriction resulting in discoloration of the skin and pain in the affected areas, often involving fingers or toes. Classically associated with triphasic color changes (white, blue, red) but may be biphasic. Often occurs in response to cold temperatures or emotional stress. May be primary or secondary to an underlying autoimmune disease.
Also known as: Raynaud disease, Raynaud syndrome, Raynaud's disease, Raynaud's syndrome, Raynaud's syndrome (disorder) [ambiguous], secondary Raynaud disease, secondary Raynaud phenomenon, secondary Raynaud's disease
15 clinical trials for this condition and its sub-types, 10 tagged with Raynaud disease itself.
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Can a home tablet catch wound infections before they send patients back to the hospital?
Prevention CompletedResearchers are testing whether a home telehealth system can prevent complications after vascular surgery that involves a groin incision. Patients scheduled for these procedures are randomly assigned to receive either standard discharge instructions or a tablet with a weight scal…
Sponsor: CAMC Health System • Aim: Prevention
Last updated Sep 11, 2026 00:00 UTC
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Can botox shots warm up cold fingers? a trial investigates
Symptom relief CompletedThis trial tests whether injecting botulinum toxin into the fingers can improve blood flow and temperature in people with Raynaud's phenomenon that has not responded to standard treatments. Participants are randomly assigned to receive a placebo, a low dose, or a higher dose of t…
Phase 4 • Sponsor: Emory University • Aim: Symptom relief
Last updated Jul 31, 2026 00:00 UTC
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Can a blood vessel drug ease Raynaud's in scleroderma?
Symptom relief CompletedThis Phase 2 trial tested whether selexipag, a drug that opens blood vessels, can reduce the number of Raynaud's attacks in adults with systemic sclerosis. 74 participants took either selexipag or a placebo twice daily. The main goal was to see if the drug lowered weekly attack f…
Phase 2 • Sponsor: Actelion • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC