RAD51D-related cancer predisposition
MONDO:0700274Hereditary cancer predisposition due to variation(s) in the RAD51D gene. Pathogenic germline variation in RAD51D confers an autosomal dominant predisposition to tumor formation at multiple primary sites, including ovarian cancer, triple negative breast cancer and ER negative breast cancer.
36 clinical trials for this condition and its sub-types, 4 tagged with RAD51D-related cancer predisposition itself.
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Could removing tubes first, ovaries later prevent ovarian cancer just as well?
Prevention Recruiting nowThis study is for women with BRCA1, BRCA2, or other gene mutations that greatly raise ovarian cancer risk. Instead of removing both ovaries and fallopian tubes at once, researchers are testing whether removing just the tubes first and delaying ovary removal is equally safe. The g…
Sponsor: University Medical Center Nijmegen • Aim: Prevention
Last updated Jun 27, 2026 12:04 UTC
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Can digital tools make cancer genetic counseling more effective?
Knowledge-focused Recruiting nowThis study looks at two new approaches to cancer genetic counseling. The first helps doctors reach out to family members who may have inherited a cancer-related gene change, making it easier for them to get tested. The second uses an online portal to keep patients and their docto…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC