Pseudomyxoma peritonei

This trial tests whether metformin, a common diabetes medication, can help people with pseudomyxoma peritonei, a rare cancer that spreads in the abdomen. The study includes adults whose cancer has returned or cannot be surgically removed. Researchers will measure how many partici…

This study tests two ways of giving heated chemotherapy directly into the abdomen during surgery for advanced gastrointestinal cancers that have spread to the lining of the belly. One method uses a fixed dose for everyone, while the other adjusts the dose based on the patient's b…

This study tests whether a concentrated clotting drug (fibrinogen) can better control major blood loss during surgery for pseudomyxoma peritonei, a rare abdominal cancer. About 90 adults will be randomly assigned to receive either the drug or a standard blood product during their…

This study tests whether a lower dose of heated chemotherapy given during surgery works as well as a higher dose for people with pseudomyxoma peritonei, a rare cancer that spreads in the abdomen. About 176 participants will be randomly assigned to receive either the lower dose ov…

This early-phase trial tests a cancer vaccine (Pseudovax) combined with an immune booster and an immunotherapy drug in 10 people with pseudomyxoma peritonei, a rare abdominal cancer that has come back or cannot be removed. The goal is to see if the treatment is safe and can react…

This study tests whether giving three rounds of heated chemotherapy directly into the abdomen after surgery works better than just one round for people with pseudomyxoma peritonei, a rare cancer that spreads in the belly. About 132 adults will be randomly assigned to one or three…

This study tests whether a daily breathing exercise called cardiac coherence can lower anxiety in people awaiting surgery for peritoneal cancer. About 60 participants will either practice the technique or receive standard care. The goal is to see if this simple, drug-free method …

This study collects follow-up data from 125 people with peritoneal surface cancers, including colorectal-origin carcinomatosis, pseudomyxoma peritonei, and peritoneal mesothelioma, who are scheduled for cytoreductive surgery combined with HIPEC. The goal is to track their outcome…

This study is building a global patient registry to collect real-world information from people diagnosed with appendix cancer or pseudomyxoma peritonei (PMP), a rare condition where tumors spread in the abdomen. Participants and caregivers share details about their symptoms, trea…

This study reviews medical records of 500 adults who had cytoreductive surgery (with or without heated chemotherapy) for advanced abdominal cancers. The goal is to find out how often incisional hernias occur and what patient or surgical factors increase the risk. Researchers hope…