Progressive familial heart block, type 1A
MONDO:0007240An autosomal dominant inherited cardiac bundle branch disorder which can progress to complete heart block.
Also known as: Lenegre's disease, PFHB1A, SCN5A progressive familial heart block, heart block, progressive, type IA, progressive familial heart block caused by mutation in SCN5A, progressive familial heart block, type IA, Cardiac conduction defect, nonprogressive, Cardiac conduction defect, progressive
53 clinical trials for this condition and its sub-types, 19 tagged with Progressive familial heart block, type 1A itself.
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New heart pacing strategy could cut defibrillator need
Disease control OngoingThis study tests whether a special heart pacing technique (left bundle branch pacing) combined with standard heart failure drugs can improve heart function better than drugs alone. It includes 50 adults with non-ischemic heart failure and a specific heart block. The main goal is …
Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New pacemaker study aims to help heart failure patients with mildly reduced pumping function
Disease control OngoingThis study is testing whether a special pacemaker (cardiac resynchronization therapy, or CRT) can improve heart function and symptoms in people with mild heart failure and a specific type of heart block called left bundle-branch block. About 21 participants will receive a CRT dev…
Sponsor: Inova Health Care Services • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Heart failure clue: blood test may forecast therapy success
Knowledge-focused OngoingThis study looks at whether a substance called YKL-40 in the blood can help predict how well heart failure patients will respond to cardiac resynchronization therapy (CRT), a special pacemaker. About 51 adults with severe heart failure will have blood samples taken during their r…
Sponsor: Trakya University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC