Prinzmetal angina
MONDO:0006021A syndrome typically consisting of angina (cardiac chest pain) at rest that occurs in cycles. It is caused by vasospasm, a narrowing of the coronary arteries caused by contraction of the smooth muscle tissue in the vessel walls rather than directly by atherosclerosis (buildup of fatty plaque and hardening of the arteries). For a portion of patients Prinzmetal's angina may be a manifestation of vasospastic disorder and is associated with migraine, Raynaud's phenomenon or aspirin-induced asthma.
Also known as: angina inversa, variant angina
90 clinical trials for this condition and its sub-types, 7 tagged with Prinzmetal angina itself.
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Shock therapy: can a heart device save lives in rare angina?
Disease control Recruiting nowThis study tests whether adding an implantable cardioverter defibrillator (ICD) to standard medication helps people with variant angina who have survived a sudden cardiac arrest. About 140 adults will be randomly assigned to get either an ICD plus medication or medication alone. …
Phase 4 • Sponsor: Kee-joon Choi • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New test during angiography could unlock better care for hidden heart pain
Knowledge-focused Recruiting nowThis study looks at people with chest pain (angina) but no major blockages in their heart arteries. During a standard angiogram, doctors will perform an extra diagnostic test to see if it helps guide treatment. Half the participants will have the test results shared with their do…
Sponsor: NHS Greater Glasgow and Clyde • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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New registry aims to unlock secrets of nerve treatment for fainting disorders
Knowledge-focused Recruiting nowThis study is a registry that collects information from 1,000 adults who have conditions like fainting, rapid heartbeat, or low blood pressure and have received a procedure that adjusts nerve signals to the heart. Researchers will track whether symptoms return within a year. The …
Sponsor: SABAMED Medical Center Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC