Primary brain neoplasm

This early-phase trial is testing whether an experimental drug called NLG802, taken as a pill, can be safely combined with the chemotherapy drug temozolomide for children and young adults (ages 5 to 21) with progressive brain or spinal cord cancer. The study aims to find the high…

This study will test whether combining PET scans with amino acid tracers and MRI can more accurately diagnose brain tumors and tell if they are growing or just reacting to treatment. Researchers will follow 270 adults with primary or secondary brain tumors, comparing the new imag…

This study tests whether a simple online computer game can help children with brain tumors think faster. 300 kids will do 15 minutes of cognitive training, 5 times a week for 8 weeks. Researchers will check if the training is easy to do at home and if it actually improves process…

This study looks at whether a personalized exercise program is doable for adults with brain tumors. Researchers will track how many patients join and stick with the 3-month program, and measure changes in quality of life, mood, and symptoms. The goal is to see if adapted physical…

This Mayo Clinic study will test whether a special ultrasound technique, called shear wave elastography, can measure how stiff brain tumors are compared to healthy brain tissue during surgery. Researchers will enroll 30 adults with newly diagnosed or recurrent brain tumors. The g…

This study will follow 40 adults with brain tumors who are scheduled for standard brain radiotherapy. Researchers will collect blood samples, perform brain scans, and give thinking and quality-of-life tests before and after treatment. The goal is to identify biological markers th…

This study follows 93 children aged 5-18 with brain tumors who are receiving radiation therapy. Researchers will track their nutrition and quality of life over time to see how they are connected. The goal is to create a nutrition plan and early warning system to help these childr…