Primary angle-closure glaucoma
MONDO:0001868An angle-closure glaucoma characterized by closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Primary angle-closure glaucoma has symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Primary angle closure glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component.
25 clinical trials for this condition and its sub-types, 14 tagged with Primary angle-closure glaucoma itself.
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Sub-types of Primary angle-closure glaucoma
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Chronic closed-angle glaucoma 7 trials
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Acute closed-angle glaucoma 1 trial
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Interval angle-closure glaucoma 0 trials
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New eye implant could reduce glaucoma drops
Disease control CompletedThis study tested a small implant called Supraflow v2.2 in 57 adults with open-angle or narrow-angle glaucoma. The implant is placed inside the eye to help drain fluid and lower eye pressure. The goal was to see if it safely reduces pressure and the need for daily eye drops over …
Sponsor: Ciliatech • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Warm IV fluid eases pain for emergency eye patients
Symptom relief CompletedThis study tested whether warming the intravenous (IV) mannitol fluid before giving it to people with sudden high eye pressure can reduce pain and improve comfort. 142 adults took part, with half getting warmed mannitol and half getting standard (room temperature) mannitol. The g…
Sponsor: Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC