Pressure-induced localized lipoatrophy

MONDO:0019556

Pressure-induced localized lipoatrophy is a rare, acquired, localized lipodystrophy characterized by band-like, horizontal, asymptomatic, lipoatrophic depressions with clinically normal overlying skin usually involving the anterolateral aspect of the thighs. An identifiable history of the repeated mechanical microtrauma due to occupational or postural habits is present.

Also known as: lipoatrophia semicircularis, semicircular lipoatrophy

3 clinical trials for this condition and its sub-types, 0 tagged with Pressure-induced localized lipoatrophy itself.

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↑ Localized lipodystrophy (4)

Including sub-types (3) Tagged with Pressure-induced localized lipoatrophy (0)

Trials to join now! 2 Completed 1

Rare fat disorder gene hunt: just 2 patients could unlock answers

Knowledge-focused Completed

This study looked for a new gene that causes hereditary lipodystrophy, a rare disease where people lose body fat and often develop diabetes and heart problems. Researchers studied DNA and cells from 2 patients who had the disease but no known genetic cause. The goal was to find t…

Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused

Last updated Jun 27, 2026 13:00 UTC

Pressure-induced localized lipoatrophy

Where it sits in the disease tree

Rare fat disorder gene hunt: just 2 patients could unlock answers