Premature aging syndrome
MONDO:0019303Changes in the organism associated with senescence, occurring at an accelerated rate.
Also known as: premature ageing, premature aging
109 clinical trials for this condition and its sub-types, 6 tagged with Premature aging syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Premature aging syndrome
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Telomere syndrome 9 trials · 92 incl. sub-types
7 sub-types
- Cirrhosis, familial 4 trials · 79 incl. sub-types Sub-types →
- Nodular regenerative hyperplasia of the liver 3 trials
- Immunodeficiency-centromeric instability-facial anomalies syndrome 1 trial Sub-types →
- Pulmonary fibrosis and/or bone marrow failure, telomere-related 1 trial Sub-types →
- ACD-related telomere biology disorder 0 trials Sub-types →
- Coats plus syndrome 0 trials Sub-types →
- Dyskeratosis congenita, autosomal dominant 1 0 trials
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Progeroid syndrome 3 trials · 11 incl. sub-types
16 sub-types
- Cockayne syndrome 6 trials Sub-types →
- Hutchinson-Gilford progeria syndrome 3 trials
- Werner syndrome 2 trials
- Fischer-Zirnsak progeroid syndrome 0 trials
- Fontaine progeroid syndrome 0 trials
- Garg-Mishra progeroid syndrome 0 trials
- Marbach-Rustad progeroid syndrome 0 trials
- Nestor-Guillermo progeria syndrome 0 trials
- RECON progeroid syndrome 0 trials
- Wiedemann-Rautenstrauch syndrome 0 trials
- XFE progeroid syndrome 0 trials
- Achalasia-progeroid syndrome 0 trials
- Mandibular hypoplasia-deafness-progeroid syndrome 0 trials
- Mandibuloacral dysplasia progeroid syndrome 0 trials
- Progeroid and marfanoid aspect-lipodystrophy syndrome 0 trials
- Progeroid facial appearance with hand anomalies 0 trials
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Flynn-Aird syndrome 0 trials
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Acrogeria 0 trials
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De Barsy syndrome 0 trials
2 sub-types
- ALDH18A1-related de Barsy syndrome 0 trials
- PYCR1-related de Barsy syndrome 0 trials
Most studied deeper sub-types
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Can two old drugs turn back the clock on aging in mental illness?
Disease control OngoingThis study tests whether a combination of dasatinib and quercetin, two drugs that clear out aging cells, can safely slow down accelerated aging in older adults with treatment-resistant depression or schizophrenia. Forty participants aged 50 and older will take the drugs and be mo…
Phase 2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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HIV study seeks clues to brain aging in Long-Term survivors
Knowledge-focused OngoingThis study follows 298 older adults with HIV in Zambia to compare brain health between those who have had HIV for a long time (7+ years) and those with a shorter infection (1-2 years). Researchers will track memory, thinking, mental health, frailty, and nerve health over 6 years.…
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC